A D Rahimtula
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Explore the profile of A D Rahimtula including associated specialties, affiliations and a list of published articles.
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53
Citations
254
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Recent Articles
1.
Omar R, Gelboin H, Rahimtula A
Biochem Pharmacol
. 1996 Feb;
51(3):207-16.
PMID: 8573185
Liver microsomes from rats treated with various P450 inducers were examined for their ability to metabolize the mycotoxin ochratoxin A (OTA) to 4(R)-4-hydroxyochratoxin A (4R), the major metabolite, and 4(S)-4-hydroxyochratoxin...
2.
Omar R, Rahimtula A
Biochem Pharmacol
. 1993 Dec;
46(11):2073-81.
PMID: 8267656
Rat liver microsomes were examined for their ability to oxidize the mycotoxin ochratoxin A (OTA) to 4(R)-4-hydroxyochratoxin A [(R)-4-OH-OTA] and 4(S)-4-hydroxyochratoxin A [(S)-4-OH-OTA] and to induce OTA-dependent lipid peroxidation. Microsomes...
3.
Chong X, Rahimtula A
Biochem Pharmacol
. 1992 Oct;
44(7):1401-9.
PMID: 1417961
A disruption of calcium homeostasis, leading to a sustained increase in cytosolic calcium levels, has been associated with cytotoxicity in response to a variety of agents in different cell types....
4.
Omar R, Randell E, Rahimtula A
J Biochem Toxicol
. 1991 Jan;
6(3):211-20.
PMID: 1770505
The mycotoxin ochratoxin A (OA) consists of 5-chloro-3-methyl-3,4-dihydro-8-hydroxyisocoumarin moiety linked by an amide bond to beta-L-phenylalanine. When added to washed rat platelets in vitro, OA caused a dose-dependent inhibition of...
5.
Omar R, Rahimtula A, Bartsch H
J Biochem Toxicol
. 1991 Jan;
6(3):203-9.
PMID: 1770504
The role of cytochrome P-450 in the stimulation of lipid peroxidation by the nephrotoxic mycotoxin ochratoxin A has been investigated. Ochratoxin A was previously shown to markedly stimulate lipid peroxidation...
6.
Rahimtula A, Chong X
IARC Sci Publ
. 1991 Jan;
(115):207-14.
PMID: 1668170
Disruption of calcium homeostasis, leading to a sustained increase in cytosolic calcium level, has been associated with cytotoxicity in response to a variety of agents in different cell types. We...
7.
Hasinoff B, Rahimtula A, Omar R
Biochim Biophys Acta
. 1990 Oct;
1036(1):78-81.
PMID: 2171659
The Fe3+ complex of ochratoxin A has been shown to produce hydroxyl radicals in the presence of NADPH and NADPH-cytochrome-P-450 reductase. ESR spin-trapping experiments carried out in the presence of...
8.
Omar R, Hasinoff B, Mejilla F, Rahimtula A
Biochem Pharmacol
. 1990 Sep;
40(6):1183-91.
PMID: 2119584
Lipid peroxidation, measured as malondialdehyde formation or by oxygen uptake, was stimulated markedly by the mycotoxin ochratoxin A (OTA) in a reconstituted system consisting of phospholipid vesicles, the flavoprotein NADPH-cytochrome...
9.
Khan S, Codner M, Payne J, Rahimtula A
Carcinogenesis
. 1989 Feb;
10(2):269-72.
PMID: 2912577
The effect of oral administration of a Prudhoe Bay crude oil (PBCO) to male rats (PBCO, 2.6 g/kg body weight, daily) for 5-12 days on hepatic and renal microsomal monooxygenase...
10.
Khan S, Martin M, Bartsch H, Rahimtula A
Biochem Pharmacol
. 1989 Jan;
38(1):67-72.
PMID: 2910308
The effect of ochratoxin A on hepatic microsomal calcium sequestration was studied both in vivo and in vitro. The rate of ATP-dependent calcium uptake was inhibited by 42-45% in ochratoxin...