A C Roberts
Overview
Explore the profile of A C Roberts including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
133
Citations
3671
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Recent Articles
1.
Axelsson S, Horst N, Horiguchi N, Roberts A, Robbins T
J Neurosci
. 2021 Jul;
41(34):7246-7258.
PMID: 34261701
Previously, studies using human neuroimaging and excitotoxic lesions in non-human primate have demonstrated an important role of ventrolateral prefrontal cortex (vlPFC) in higher order cognitive functions such as cognitive flexibility...
2.
Quah S, McIver L, Roberts A, Santangelo A
J Neurosci
. 2020 May;
40(24):4739-4749.
PMID: 32393533
High trait anxiety is associated with altered activity across emotion regulation circuitry and a higher risk of developing anxiety disorders and depression. This circuitry is extensively modulated by serotonin. Here,...
3.
Sawiak S, Shiba Y, Oikonomidis L, Windle C, Santangelo A, Grydeland H, et al.
Cereb Cortex
. 2018 Oct;
28(12):4440-4453.
PMID: 30307494
With increasing attention on the developmental causes of neuropsychiatric disorders, appropriate animal models are crucial to identifying causes and assessing potential interventions. The common marmoset is an ideal model as...
4.
Clarke H, Cardinal R, Rygula R, Hong Y, Fryer T, Sawiak S, et al.
J Neurosci
. 2014 May;
34(22):7663-76.
PMID: 24872570
Schizophrenia is associated with upregulation of dopamine (DA) release in the caudate nucleus. The caudate has dense connections with the orbitofrontal cortex (OFC) via the frontostriatal loops, and both areas...
5.
Man M, Dalley J, Roberts A
Cereb Cortex
. 2009 Nov;
20(7):1668-75.
PMID: 19903764
Central serotonin is implicated in a variety of emotional and behavioral control processes. Serotonin depletion can lead to exaggerated aversive processing and deficient response inhibition, effects that have been linked...
6.
Wai P, Ruby J, Davis K, Roberts A, Roberts K
Hernia
. 2009 Mar;
13(5):559-63.
PMID: 19280274
Background: Laparoscopic ventral hernia repair in comparison to open herniorrhaphy results in reduced length of stay, less post-operative pain, earlier return to work, and reduced complications for the repair of...
7.
Walker S, Robbins T, Roberts A
Cereb Cortex
. 2008 Aug;
19(4):889-98.
PMID: 18723695
We have shown previously that the inhibitory control functions of the orbitofrontal cortex (OFC) are disrupted by serotonin, but not dopamine depletions. However, both dopamine and serotonin terminals and receptors...
8.
Man M, Clarke H, Roberts A
Cereb Cortex
. 2008 Aug;
19(4):899-906.
PMID: 18689858
An impairment in learning to inhibit prepotent responses to positive stimuli is associated with damage to the orbitofrontal cortex (OFC) in rats, monkeys, and humans performing discrimination reversal, extinction, and...
9.
Reekie Y, Braesicke K, Man M, Roberts A
Proc Natl Acad Sci U S A
. 2008 Jul;
105(28):9787-92.
PMID: 18621690
Successful adaptation to changes in an animal's emotional and motivational environment depends on behavioral flexibility accompanied by changes in bodily responses, e.g., autonomic and endocrine, which support the change in...
10.
Robbins T, Roberts A
Cereb Cortex
. 2007 Nov;
17 Suppl 1:i151-60.
PMID: 17725997
The prefrontal cortex (PFC) is innervated by the monoamines, dopamine (DA), noradrenaline (NA), and serotonin, as well as acetylcholine, and the marked influence of these neurochemical systems on prefrontal working...