A C McDonald
Overview
Explore the profile of A C McDonald including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
28
Citations
584
Followers
0
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Recent Articles
1.
Elander N, Aughton K, Ghaneh P, Neoptolemos J, Palmer D, Cox T, et al.
Br J Cancer
. 2018 Mar;
118(8):1084-1088.
PMID: 29523831
Background: Deoxycytidylate deaminase (DCTD) and ribonucleotide reductase subunit M1 (RRM1) are potential prognostic and predictive biomarkers for pyrimidine-based chemotherapy in pancreatic adenocarcinoma. Methods: Immunohistochemical staining of DCTD and RRM1 was...
2.
Expression of dihydropyrimidine dehydrogenase (DPD) and hENT1 predicts survival in pancreatic cancer
Elander N, Aughton K, Ghaneh P, Neoptolemos J, Palmer D, Cox T, et al.
Br J Cancer
. 2018 Mar;
118(7):947-954.
PMID: 29515256
Background: Dihydropyrimidine dehydrogenase (DPD) tumour expression may provide added value to human equilibrative nucleoside transporter-1 (hENT1) tumour expression in predicting survival following pyrimidine-based adjuvant chemotherapy. Methods: DPD and hENT1 immunohistochemistry...
3.
McGowan H, Schuijers J, Grills B, McDonald S, Rickard J, Silke J, et al.
J Musculoskelet Neuronal Interact
. 2014 Dec;
14(4):454-63.
PMID: 25524971
Objectives: SHARPIN is a subunit of LUBAC and regulates activation of NF-κB, a pivotal transcription factor in skeletal homeostasis. Mutated SHARPIN gene (cpdm) mice develop chronic proliferative dermatitis and systemic...
4.
McGowan H, Schuijers J, Grills B, McDonald S, McDonald A
J Musculoskelet Neuronal Interact
. 2014 Jun;
14(2):162-72.
PMID: 24879020
Objectives: Previous studies have shown galanin (GAL) injections onto mouse calvaria increased bone thickness and osteoblast number. This study investigated the effects of the GAL receptor agonist galnon on bone...
5.
Carruthers R, Tho L, Brown J, Kakumanu S, McCartney E, McDonald A
Colorectal Dis
. 2012 Jun;
14(10):e701-7.
PMID: 22731833
Aim: Current management of locally advanced rectal cancer includes neoadjuvant chemoradiation in selected patients to increase the chance of a tumour-free circumferential resection margin. There is uncertainty over the role...
6.
Chiodini J, Anderson E, Driver C, Field V, Flaherty G, Grieve A, et al.
Travel Med Infect Dis
. 2012 Jun;
10(3):109-28.
PMID: 22658381
Travel Medicine has emerged as a distinct entity over the last two decades in response to a very substantial increase in international travel and is now forging its own identity,...
7.
Low G, Tho L, Leen E, Wiebe E, Kakumanu S, McDonald A, et al.
Surgeon
. 2008 Aug;
6(4):222-31.
PMID: 18697365
Developments in rectal cancer imaging have revolutionised the management of this condition. It has become increasingly important for oncologists and surgeons to have a working insight into radiological assessment in...
8.
Sun Myint A, Grieve R, McDonald A, Levine E, Ramani S, Perkins K, et al.
Clin Oncol (R Coll Radiol)
. 2007 Sep;
19(9):674-81.
PMID: 17888639
With the introduction of colorectal screening in the UK, more patients will probably be diagnosed with early rectal cancer. The UK has an increasingly elderly population and not all patients...
9.
McDonald A, Schuijers J, Gundlach A, Grills B
Bone
. 2006 Dec;
40(4):895-903.
PMID: 17157570
We have previously shown that after bone fracture, galanin (GAL) and GAL receptor expression is increased in osteoblast-like cells of callus; however, the role of elevated GAL/GAL receptors in this...
10.
Crumley A, McMillan D, McKernan M, McDonald A, Stuart R
Br J Cancer
. 2006 Feb;
94(5):637-41.
PMID: 16479253
There is increasing evidence that the presence of an ongoing systemic inflammatory response is associated with poor outcome in patients with advanced cancer. The aim of the present study was...