A C Holloway
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Explore the profile of A C Holloway including associated specialties, affiliations and a list of published articles.
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30
Citations
358
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Recent Articles
11.
Holloway A, Anger D, Crankshaw D, Wu M, Foster W
J Appl Toxicol
. 2007 Aug;
28(3):260-70.
PMID: 17685393
Atrazine (ATR) is a pesticide used widely throughout North America. Although not directly estrogenic, ATR treatment has been shown to increase aromatase activity in tumor cell lines. Thus, it is...
12.
Holloway A, Petrik J, Younglai E
Reprod Toxicol
. 2007 Jun;
24(3-4):359-64.
PMID: 17574386
1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE, DDE), a metabolite of DDT is a persistent hormonally active environmental toxicant present in human serum and follicular fluid. The objective of this study was to investigate the...
13.
Fetal and neonatal exposure to nicotine disrupts ovarian function and fertility in adult female rats
Holloway A, Kellenberger L, Petrik J
Endocrine
. 2007 Feb;
30(2):213-6.
PMID: 17322582
Women born to mothers who smoked during pregnancy have been shown to have impaired fertility, although the mechanisms underlying this association are unknown. Nicotine administration in adult animals has adverse...
14.
Whittle W, Holloway A, Lye S, Challis J, Gibb W
J Soc Gynecol Investig
. 2006 Sep;
13(7):506-11.
PMID: 16990030
Background: We have recently described two distinct pathways of intrauterine prostaglandin (PG) synthesis: a cortisol-dependent/estradiol-independent mechanism within trophoblast tissue leading to elevations in fetal plasma PGE2, and an estradiol-dependent mechanism...
15.
Holloway A, Lim G, Petrik J, Foster W, Morrison K, Gerstein H
Diabetologia
. 2005 Nov;
48(12):2661-6.
PMID: 16270195
Aims/hypothesis: Epidemiological studies report an increased risk of obesity and type 2 diabetes in children born to women who smoked during pregnancy. This study examines the effect of fetal and...
16.
Miller M, Holloway A, Foster W
Clin Exp Metastasis
. 2005 Aug;
22(2):149-56.
PMID: 16086235
Benzo-[a]-pyrene (B[a]P), a carcinogenic component of cigarette smoke, has been shown to increase both COX-II expression and prostaglandin output in vascular smooth muscle and oral epithelial cells. In addition, invasive...
17.
Gupta S, Alfaidy N, Holloway A, Whittle W, Lye S, Gibb W, et al.
J Endocrinol
. 2003 Jan;
176(2):175-84.
PMID: 12553866
In the late-gestation sheep, increased fetal plasma cortisol concentration and placental oestradiol (E(2)) output contribute to fetal organ maturation, in addition to the onset of parturition. Both cortisol and E(2)...
18.
Giannoulias D, Alfaidy N, Holloway A, Gibb W, Sun M, Lye S, et al.
J Clin Endocrinol Metab
. 2002 Nov;
87(11):5274-82.
PMID: 12414902
Prostaglandins (PGs) act as potent uterotonins at the time of labor. Prostaglandin E synthase (PGES) is responsible for the formation of PGE(2), a uterotonin. PGI(2) is synthesized by the prostaglandin...
19.
Martin R, Whittle W, Holloway A, Gyomorey S, Gibb W, Lye S, et al.
Biol Reprod
. 2002 Aug;
67(3):868-73.
PMID: 12193396
Recent evidence suggests that ovine placental output of prostaglandin (PG) E2 rises through late gestation partly because of a direct effect of cortisol on PGH2 synthase 2 (PGHS-2) expression and...
20.
Giannoulias D, Patel F, Holloway A, Lye S, Tai H, Challis J
J Clin Endocrinol Metab
. 2002 Mar;
87(3):1345-52.
PMID: 11889207
Prostaglandins (PGs) play a key role in the onset of labor in many species and regulate uterine contractility and cervical dilatation. Therefore, the regulation of prostaglandin output by PG synthesizing...