A C Ferguson-Smith
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Explore the profile of A C Ferguson-Smith including associated specialties, affiliations and a list of published articles.
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48
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1811
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Recent Articles
1.
Ferron S, Radford E, Domingo-Muelas A, Kleine I, Ramme A, Gray D, et al.
Nat Commun
. 2015 Sep;
6:8265.
PMID: 26369386
Genomic imprinting is implicated in the control of gene dosage in neurogenic niches. Here we address the importance of Igf2 imprinting for murine adult neurogenesis in the subventricular zone (SVZ)...
2.
Fogarty N, Burton G, Ferguson-Smith A
Placenta
. 2015 May;
36(8):796-802.
PMID: 26008948
Introduction: The syncytiotrophoblast (STB) epithelial covering of the villous tree in the human placenta is a multi-nucleated syncytium that is sustained by continuous incorporation of differentiating cytotrophoblast (CTB) cells. STB...
3.
Charalambous M, da Rocha S, Hernandez A, Ferguson-Smith A
Acta Physiol (Oxf)
. 2013 Sep;
210(1):174-87.
PMID: 24034272
Aim: Disruption to insulin-like growth factor (IGF) signalling pathways during early life causes growth retardation and defects of developing metabolic organs that can alter set points of energy homeostasis for...
4.
van der Weyden L, Rust A, McIntyre R, Robles-Espinoza C, Del Castillo Velasco-Herrera M, Strogantsev R, et al.
Oncogene
. 2012 Feb;
32(3):397-402.
PMID: 22370638
We performed a genetic screen in mice to identify candidate genes that are associated with leukaemogenesis in the context of Trp53 heterozygosity. To do this we generated Trp53 heterozygous mice...
5.
Fogarty N, Mayhew T, Ferguson-Smith A, Burton G
J Anat
. 2011 Sep;
219(5):601-10.
PMID: 21883201
The syncytiotrophoblast (STB) epithelial covering of the human placenta is a unique terminally differentiated, multi-nucleated syncytium. No mitotic bodies are observed in the STB, which is sustained by continuous fusion...
6.
Lim A, Ferguson-Smith A
Semin Cell Dev Biol
. 2009 Nov;
21(2):201-8.
PMID: 19879952
Genomic imprinting in gametogenesis marks a subset of mammalian genes for parent-of-origin-dependent monoallelic expression in the offspring. In mice, the identification and manipulation of individual imprinted genes has shown that...
7.
Ellery P, Cindrova-Davies T, Jauniaux E, Ferguson-Smith A, Burton G
Placenta
. 2009 Feb;
30(4):329-34.
PMID: 19215981
The aim was to test for evidence of transcriptional activity within the nuclei of the syncytiotrophoblast of the human placenta. The syncytiotrophoblast forms the epithelial covering of the villous tree,...
8.
Coan P, Fowden A, Constancia M, Ferguson-Smith A, Burton G, Sibley C
J Physiol
. 2008 Aug;
586(20):5023-32.
PMID: 18755750
Both complete knockout of the Igf2 gene (Igf2null(+/-)) and knockout of its placental specific transcript alone (Igf2P0(+/-)) lead to fetal growth restriction in mice. However, in the Igf2null(+/-) this growth...
9.
Burdon C, Mann C, Cindrova-Davies T, Ferguson-Smith A, Burton G
Placenta
. 2007 Jan;
28(7):724-33.
PMID: 17222904
Placental oxidative stress has been implicated in many complications of human pregnancy, including preterm delivery and preeclampsia. It is now appreciated that reactive oxygen species can induce a spectrum of...
10.
Coan P, Conroy N, Burton G, Ferguson-Smith A
Dev Dyn
. 2006 Oct;
235(12):3280-94.
PMID: 17039549
The junctional zone (Jz) of the mouse placenta consists of two main trophoblast populations, spongiotrophoblasts and glycogen cells (GCs), but the development and function of both cell types are unknown....