A C Alfrey
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Explore the profile of A C Alfrey including associated specialties, affiliations and a list of published articles.
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Articles
140
Citations
1593
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Recent Articles
1.
Lufkin E, Alfrey A, Trucksess M, Holmes J
Urology
. 2011 Feb;
4(1):5-12.
PMID: 21322975
A unique family study is presented, representing 124 members in four generations. Sixty-four patients were studied clinically, and 31 were found to have sonographic evidence of polycystic kidney disease. Findings...
2.
Naylor K, Eastell R, Shattuck K, Alfrey A, Klein G
Pediatr Res
. 1999 Mar;
45(3):363-6.
PMID: 10088655
Total parenteral nutrition is associated with osteopenia in preterm infants. Insufficient calcium and phosphate are likely causes: aluminum contamination is another possible contributing factor as this adversely affects bone formation...
3.
Flaten T, Alfrey A, Birchall J, Savory J, Yokel R
J Toxicol Environ Health
. 1996 Aug;
48(6):527-41.
PMID: 8772797
A wide range of toxic effects of aluminum (Al) have been demonstrated in plants and aquatic animals in nature, in experimental animals by several routes of exposure, and under different...
4.
Sponsel H, Alfrey A, HAMMOND W, Durr J, Ray C, Anderson R
Kidney Int
. 1996 Aug;
50(2):436-44.
PMID: 8840271
Since iron has been implicated as a potential nephrotoxin, we examined the effect of iron on several aspects of cultured renal tubular epithelial cell biology. We found that exposure to...
5.
Cooper M, Buddington B, Miller N, Alfrey A
Am J Kidney Dis
. 1995 Feb;
25(2):314-9.
PMID: 7531396
In nephrotic syndrome, iron is presented to the tubule fluid in a nonreactive form in association with transferrin as a result of the glomerular protein leak. At an alkaline pH,...
6.
Nolan C, DeGoes J, Alfrey A
South Med J
. 1994 Sep;
87(9):894-8.
PMID: 8091252
Animal models suggest that citrate-containing compounds augment absorption of aluminum from food and tap water, causing aluminum accumulation in bone and brain despite normal renal function. Citrate also enhances lead...
7.
LEYSSAC P, Frederiksen O, Holstein-Rathlou N, Alfrey A, Christensen P
Am J Physiol
. 1994 Jul;
267(1 Pt 2):F86-93.
PMID: 8048569
We tested the hypothesis that proximal tubular Li+ reabsorption is due to passive transport. Clearances of [14C]inulin (CIn) and Li+ (CLi), proximal transepithelial electrical potential difference (PD), and tubular fluid-to-plasma...
8.
Klein G, Herndon D, Rutan T, Barnett J, Miller N, Alfrey A
J Burn Care Rehabil
. 1994 Jul;
15(4):354-8.
PMID: 7929518
Severely burned patients experience a bone lesion consisting of markedly reduced bone formation and evidence of decreased resportion. The cause of the lesion may be multifactorial, but aluminum loading, which...
9.
Alfrey A
Am J Kidney Dis
. 1994 Feb;
23(2):183-7.
PMID: 8311072
As nephron population is lost from injury or disease the remaining nephrons undergo functional and anatomic hypertrophy. The compensatory or secondary events responsible for these changes may exert a detrimental...
10.
Alfrey A
Ther Drug Monit
. 1993 Dec;
15(6):593-7.
PMID: 8122300
During the past two decades, in association with the commencement of chronic dialysis therapy and prolongation of the uremic state, aluminum toxicity has represented a major cause of morbidity and...