A Buntinx
Overview
Explore the profile of A Buntinx including associated specialties, affiliations and a list of published articles.
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19
Citations
230
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Recent Articles
1.
Zoethout R, Iannone R, Bloem B, Palcza J, Murphy G, Chodakewitz J, et al.
J Psychopharmacol
. 2011 Feb;
26(2):292-302.
PMID: 21335358
Essential tremor (ET) is a common movement disorder. Animal studies show that histaminergic modulation may affect the pathological processes involved in the generation of ET. Histamine-3 receptor inverse agonists (H3RIA)...
2.
Van Hecken A, SCHWARTZ J, Depre M, De Lepeleire I, Dallob A, Tanaka W, et al.
J Clin Pharmacol
. 2000 Oct;
40(10):1109-20.
PMID: 11028250
Steady-state inhibitory activity of rofecoxib (Vioxx) on COX-2 versus COX-1 was compared with that of commonly used nonsteroidal anti-inflammatory drugs (NSAIDs) in 76 healthy volunteers randomized to placebo, rofecoxib 12.5...
3.
Depre M, Friedman B, Tanaka W, Van Hecken A, Buntinx A, DESCHEPPER P
Clin Pharmacol Ther
. 1993 May;
53(5):602-7.
PMID: 8387904
MK-886, a leukotriene biosynthesis inhibitor, was evaluated in double-blind, placebo-controlled, randomized single- and multiple-dose studies in 12 and 24 healthy male subjects, respectively. The effects of a single dose (250,...
4.
Friedman B, Bel E, Buntinx A, Tanaka W, Han Y, Shingo S, et al.
Am Rev Respir Dis
. 1993 Apr;
147(4):839-44.
PMID: 8385430
To elucidate the role of leukotrienes (LT) in allergic asthma in humans the effect of MK-886, an LT biosynthesis inhibitor, was evaluated on antigen-induced early (EAR) and late (LAR) asthmatic...
5.
Depre M, Meeter C, Van Hecken A, Laskin O, Buntinx A, De Schepper P
Clin Pharmacol Ther
. 1992 Oct;
52(4):409-12.
PMID: 1424413
A four-period, two-panel single rising-dose study (0.1 to 100 mg) was conducted in healthy men to investigate the pharmacodynamics and tolerability of L-654,066, a steroid 5 alpha-reductase inhibitor. Within each...
6.
Lammers J, Van Daele P, Van den Elshout F, Decramer M, Buntinx A, De Lepeleire I, et al.
Pulm Pharmacol
. 1992 Jun;
5(2):121-5.
PMID: 1611229
The safety, tolerability and bronchodilator properties of inhaled verlukast (MK-0679), a new potent and selective LTD4-receptor antagonist, were studied in 12 asthmatic subjects with more than 15% increase in FEV1...
7.
Depre M, Margolskee D, Van Hecken A, Hsieh J, Buntinx A, De Schepper P, et al.
Eur J Clin Pharmacol
. 1992 Jan;
43(4):431-3.
PMID: 1451726
The disposition of the enantiomers of MK-571 (MK-0679 and L-668,018) following single i.v. doses of MK-571 (L-660,711) was studied in a three way cross-over study in 12 healthy male volunteers....
8.
Depre M, Margolskee D, Hsieh J, Van Hecken A, Buntinx A, De Lepeleire I, et al.
Eur J Clin Pharmacol
. 1992 Jan;
43(4):427-30.
PMID: 1451725
We have studied the tolerability and plasma drug profiles of a leukotriene D4 receptor antagonist, MK-571, given intravenously and as an oral solution in two separate trials. Study I (i.v.)...
9.
Gunning F, Bechetoille A, Lippa E, Pfeiffer N, Gerling J, Holder D, et al.
Eye (Lond)
. 1992 Jan;
6 ( Pt 5):525-9.
PMID: 1286720
Sezolamide, a potent topical carbonic anhydrase inhibitor previously known as MK-417, was studied to determine its ocular hypotensive activity in patients with elevated intraocular pressure while on continuing therapy with...
10.
Kips J, Joos G, De Lepeleire I, Margolskee D, Buntinx A, Pauwels R, et al.
Am Rev Respir Dis
. 1991 Sep;
144(3 Pt 1):617-21.
PMID: 1892302
MK-571 is a novel leukotriene D4/E4 (LTD4/E4) receptor antagonist. The ability of MK-571 to inhibit LTD4-induced bronchoconstriction was examined both in six healthy volunteers and in six asthmatic subjects in...