A B van Spriel
Overview
Explore the profile of A B van Spriel including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
587
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Recent Articles
1.
Hontelez S, Sanecka A, Netea M, van Spriel A, Adema G
Cell Microbiol
. 2012 Jan;
14(4):467-74.
PMID: 22233321
The identification of a major class of innate immune receptors, termed pattern recognition receptors (PRRs), has boosted research on innate pathogen recognition. The immune response to a specific pathogen is...
2.
Wright M, Moseley G, van Spriel A
Tissue Antigens
. 2004 Oct;
64(5):533-42.
PMID: 15496196
A contemporary goal of researchers in leucocyte signalling has been to uncover how cells physically organize and compartmentalize signalling molecules into efficient, regulated signalling networks. This work has revealed important...
3.
van Spriel A
Curr Drug Targets Cardiovasc Haematol Disord
. 2003 Jul;
3(3):209-17.
PMID: 12871039
Infectious diseases still represent a major cause of mortality in man. Failure of the immune system to eradicate pathogens may result in serious invasive infections. Increasing numbers of immunocompromised patients,...
4.
van Spriel A, van de Winkel J
J Biol Regul Homeost Agents
. 2001 Aug;
15(2):179-81.
PMID: 11501978
No abstract available.
5.
Hellwig S, van Spriel A, Schellekens J, Mooi F, van de Winkel J
Infect Immun
. 2001 Jul;
69(8):4846-50.
PMID: 11447159
Infection with Bordetella pertussis, the causative agent of pertussis (whooping cough) in humans, is followed by the production of antibodies of several isotypes, including immunoglobulin A (IgA). Little is known,...
6.
van Spriel A, van de Winkel J
J Immunol
. 2001 Jun;
166(12):7019-22.
PMID: 11390445
Invasive candidiasis represents a life-threatening disease for immunocompromised patients. This study focused on new immunotherapeutic approaches for systemic Candida albicans infections in a human FcgammaRI-transgenic mouse model. FcgammaRI (CD64) is...
7.
van Egmond M, van Spriel A, VerMeulen H, Huls G, van Garderen E, van de Winkel J
Cancer Res
. 2001 May;
61(10):4055-60.
PMID: 11358825
Antibodies can efficiently induce antitumor responses via recruitment of Fc receptor-bearing cytotoxic cells. Polymorphonuclear (PMN) cells represent attractive effector cells for antibody-directed immunotherapy. This, because activated PMN cells coexpress the...
8.
Kobayashi T, Yamamoto K, Sugita N, van Spriel A, Kaneko S, van de Winkel J, et al.
Infect Immun
. 2001 Apr;
69(5):2935-42.
PMID: 11292709
Porphyromonas gingivalis has been implicated as a causative pathogen in periodontitis. Immunotherapeutic approaches have recently been suggested to aid in the clearance of P. gingivalis from disease sites. Because antibody-Fc...
9.
van Spriel A, Leusen J, van Egmond M, Dijkman H, Assmann K, Mayadas T, et al.
Blood
. 2001 Apr;
97(8):2478-86.
PMID: 11290613
Receptors for human immunoglobulin (Ig)G and IgA initiate potent cytolysis of antibody (Ab)-coated targets by polymorphonuclear leukocytes (PMNs). Mac-1 (complement receptor type 3, CD11b/CD18) has previously been implicated in receptor...
10.
van Egmond M, Damen C, van Spriel A, Vidarsson G, van Garderen E, van de Winkel J
Trends Immunol
. 2001 Mar;
22(4):205-11.
PMID: 11274926
IgA has traditionally been regarded a non-inflammatory antibody. This might indeed be true for secretory IgA (SIgA), which exerts its function at mucosal surfaces where commensal microorganisms and dietary antigens...