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A B Niculescu

Explore the profile of A B Niculescu including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 1095
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Recent Articles
1.
Bhagar R, Gill S, Le-Niculescu H, Yin C, Roseberry K, Mullen J, et al.
Transl Psychiatry . 2024 Sep; 14(1):362. PMID: 39242534
Suicidality remains a clear and present danger in society in general, and for mental health patients in particular. Lack of widespread use of objective and/or quantitative information has hampered treatment...
2.
Hill M, Gill S, Le-Niculescu H, MacKie O, Bhagar R, Roseberry K, et al.
Mol Psychiatry . 2024 Feb; 29(5):1528-1549. PMID: 38326562
Psychosis occurs inside the brain, but may have external manifestations (peripheral molecular biomarkers, behaviors) that can be objectively and quantitatively measured. Blood biomarkers that track core psychotic manifestations such as...
3.
Bhagar R, Le-Niculescu H, Roseberry K, Kosary K, Daly C, Ballew A, et al.
Discov Ment Health . 2023 Oct; 3(1):10. PMID: 37861857
Popular culture and medical lore have long postulated a connection between full moon and exacerbations of psychiatric disorders. We wanted to empirically analyze the hypothesis that suicides are increased during...
4.
Roseberry K, Le-Niculescu H, Levey D, Bhagar R, Soe K, Rogers J, et al.
Mol Psychiatry . 2023 Mar; 28(7):2894-2912. PMID: 36878964
Anxiety disorders are increasingly prevalent, affect people's ability to do things, and decrease quality of life. Due to lack of objective tests, they are underdiagnosed and sub-optimally treated, resulting in...
5.
Cheng M, Roseberry K, Choi Y, Quast L, Gaines M, Sandusky G, et al.
Discov Ment Health . 2022 Jun; 2(1):13. PMID: 35722470
Supplementary Information: The online version contains supplementary material available at 10.1007/s44192-022-00016-z.
6.
Le-Niculescu H, Roseberry K, Gill S, Levey D, Phalen P, Mullen J, et al.
Mol Psychiatry . 2021 Apr; 26(7):2776-2804. PMID: 33828235
Mood disorders (depression, bipolar disorders) are prevalent and disabling. They are also highly co-morbid with other psychiatric disorders. Currently there are no objective measures, such as blood tests, used in...
7.
Niculescu A, Le-Niculescu H, Roseberry K, Wang S, Hart J, Kaur A, et al.
Mol Psychiatry . 2019 Dec; 25(8):1651-1672. PMID: 31792364
Short-term memory dysfunction is a key early feature of Alzheimer's disease (AD). Psychiatric patients may be at higher risk for memory dysfunction and subsequent AD due to the negative effects...
8.
Niculescu A, Le-Niculescu H
Mol Psychiatry . 2019 Aug; 25(1):19-21. PMID: 31383925
Recent genetic studies for suicidality, including four independent GWAS, have not reproduced each other's top implicated genes. While arguments of heterogeneity, methodology, and sample sizes can be invoked, heterogeneity is...
9.
Le-Niculescu H, Roseberry K, Levey D, Rogers J, Kosary K, Prabha S, et al.
Mol Psychiatry . 2019 Mar; 25(5):918-938. PMID: 30862937
The biological fingerprint of environmental adversity may be key to understanding health and disease, as it encompasses the damage induced as well as the compensatory reactions of the organism. Metabolic...
10.
Niculescu A, Le-Niculescu H, Levey D, Roseberry K, Soe K, Rogers J, et al.
Mol Psychiatry . 2019 Feb; 24(4):501-522. PMID: 30755720
We endeavored to identify objective blood biomarkers for pain, a subjective sensation with a biological basis, using a stepwise discovery, prioritization, validation, and testing in independent cohorts design. We studied...