A A Epenetos
Overview
Explore the profile of A A Epenetos including associated specialties, affiliations and a list of published articles.
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Articles
149
Citations
1027
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Recent Articles
1.
Constantinou A, Epenetos A, Hreczuk-Hirst D, Jain S, Wright M, Chester K, et al.
Bioconjug Chem
. 2009 May;
20(5):924-31.
PMID: 19402707
Protein pharmacokinetic modulation is becoming an important tool in the development of biotherapeutics. Proteins can be chemically or recombinantly modified to alter their half-lives and bioavailability to suit particular applications...
2.
Pericleous L, Richards J, Epenetos A, Courtenay-Luck N, Deonarain M
Br J Cancer
. 2005 Nov;
93(11):1257-66.
PMID: 16265351
The humanised HMFG-1 immunoglobulin has been extensively developed as a clinical immunotherapeutic agent for MUC1 expressing tumours. We have constructed a single-chain Fv (scFv) and Fab fragment from this antibody...
3.
Zbar A, Thomas H, Wilkinson R, Wadhwa M, Syrigos K, Ross E, et al.
Int J Colorectal Dis
. 2005 May;
20(5):403-14.
PMID: 15864608
Background And Aims: The aim was to determine the toxicity, clinical and immune responses to the murine monoclonal anti-carcinoembryonic antigen (CEA) antibody, PR1A3, in patients with advanced colorectal cancer. Materials...
4.
Kalofonos H, Karamouzis M, Epenetos A
Acta Oncol
. 2001 Oct;
40(5):549-57.
PMID: 11669325
The use of radiolabeled monoclonal antibodies (MoAbs) has significantly improved the ability to detect tumor antigens, thus improving in vivo tumor diagnosis and treatment. The management of ovarian carcinoma still...
5.
Epenetos A, Hird V, Lambert H, Mason P, Coulter C
Int J Gynecol Cancer
. 2001 Mar;
10(S1):44-46.
PMID: 11240732
PURPOSE: To determine the long term survival of patients with advanced ovarian cancer treated with radioimmunotherapy following cytoreductive surgery and platinum based chemotherapy. PATIENTS AND METHODS: Eligibility criteria included patients...
6.
Linardou H, Epenetos A, Deonarain M
Int J Cancer
. 2000 May;
86(4):561-9.
PMID: 10797272
A number of mammalian proteins with suitable biological activities have been considered for use in targeted tumour therapy. Deoxyribonuclease-I (DNase-I), an endonuclease that degrades double-stranded DNA, represents an attractive candidate...
7.
Koumarianou A, Hudson M, Williams R, Epenetos A, Stamp G
Br J Cancer
. 1999 Oct;
81(3):431-9.
PMID: 10507767
To overcome the disadvantages of bi-specific antibody methodologies in vivo, a novel antibody approach has been designed to improve tumour targeting and effector to target ratio. The technique involves biotinylated...
8.
Syrigos K, Deonarian D, Epenetos A
Hybridoma
. 1999 Sep;
18(3):219-24.
PMID: 10475235
Although the management of cancer by exploiting properties distinguishing neoplastic and normal cells has always been an attractive concept, it was the development of hybridoma technology and the resulting tumor-associated...
9.
Kalofonos H, Giannakenas C, Kosmas C, Apostolopoulos D, Onienadum A, Petsas T, et al.
Acta Oncol
. 1999 Jul;
38(5):629-34.
PMID: 10427953
The targeting potential of three different monoclonal antibodies (MAbs) was assessed in patients with ovarian cancer. HMFG1, OC-125 and H17E2 labelled with 111In or 123I were evaluated prospectively for their...
10.
Intravesical administration of radiolabelled tumour-associated monoclonal antibody in bladder cancer
Syrigos K, Khawaja M, Krausz T, Williams G, Epenetos A
Acta Oncol
. 1999 Jun;
38(3):379-82.
PMID: 10380831
Considerable progress has been made over the past decade in the use of tumour-associated monoclonal antibodies (mAbs) as carriers of cytotoxic agents in the management of several malignancies. In the...