Pediatric Liver Tumors
Overview
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An infant or child who presents with a large intrahepatic mass will most likely have a malignant tumor. In children, benign tumors constitute only 30% of liver tumors and most are vascular in origin. Treatment of benign vascular tumors is conservative and seldom surgical. Hepatoblastoma is the most common malignant tumor followed by hepatocellular carcinoma. Treatment of malignant tumors is based on a combination of surgery and chemotherapy. Children with hepatic malignancies that can be resected have an excellent prognosis. Other rare benign and malignant tumors of the liver do occur and surgery plays a critical role in management.
The role of liver transplantation in the care of primary hepatic vascular tumours in children.
Grimaldi C, de Ville de Goyet J, Bici K, Cianci M, Callea F, Morabito A Front Oncol. 2022; 12:1026232.
PMID: 36505841 PMC: 9730342. DOI: 10.3389/fonc.2022.1026232.
Lu Z, Xu H, Yu X, Wang Y, Huang L, Jin X Exp Ther Med. 2018; 15(2):1277-1284.
PMID: 29434714 PMC: 5776618. DOI: 10.3892/etm.2017.5594.
A Clinicopathological Study of Paediatric Liver Tumours in a Tertiary Care Hospital.
Muthuvel E, Chander V, Srinivasan C J Clin Diagn Res. 2017; 11(3):EC50-EC53.
PMID: 28511396 PMC: 5427322. DOI: 10.7860/JCDR/2017/24223.9592.
Geller J, Kasahara M, Martinez M, Soresina A, Kashanian F, Endrikat J Magn Reson Insights. 2016; 9:21-8.
PMID: 27478381 PMC: 4957604. DOI: 10.4137/MRI.S39091.
Abdominal transplantation for unresectable tumors in children: the zooming out principle.
Samuk I, Tekin A, Tryphonopoulos P, Pinto I, Garcia J, Weppler D Pediatr Surg Int. 2015; 32(4):337-46.
PMID: 26711121 DOI: 10.1007/s00383-015-3852-3.