Cryptococcus Neoformans Var. Grubii: Separate Varietal Status for Cryptococcus Neoformans Serotype A Isolates

Overview

Journal J Clin Microbiol

Specialty Microbiology

Date 1999 Feb 13

PMID 9986871

Citations 115

Authors

S P Franzot

I F Salkin

A Casadevall

Affiliations

Soon will be listed here.

Abstract

Cryptococcus neoformans var. neoformans presently includes isolates which have been determined by the immunologic reactivity of their capsular polysaccharides to be serotype A and those which have been determined to be serotype D. However, recent analyses of the URA5 sequences and DNA fingerprinting patterns suggest significant genetic differences between the two serotypes. Therefore, we propose to recognize these genotypic distinctions, as well as previously reported phenotypic differences, by restricting C. neoformans var. neoformans to isolates which are serotype D and describing a new variety, C. neoformans var. grubii, for serotype A isolates.

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