[Lipid A Antibody Titers in Crohn's Disease (author's Transl)]

Overview

Journal Klin Wochenschr

Specialty General Medicine

Date 1976 Nov 1

PMID 994458

Citations 3

Authors

P Schussler

W Kruis

W Marget

Affiliations

Soon will be listed here.

Abstract

Lipid A antibody titers and O antibody titers against E. coli were determined in 18 patients with Crohn's disease, 28 patients with ulcerative colitis, 24 patients with acute enteritis and in 68 healthy adults. The patients with Crohn's disease showed a statistically significant elevation of the lipid A antibody titers and of the O antibody titers against E. coli compared with each of the three other groups investigated. The results could be indicative of bacterial involvement in the pathogenesis of Crohn's disease. The determination of lipid A antibody titers may be useful for the differential diagnosis between Crohn's disease and ulcerative colitis.

Citing Articles

Circulating lipid A antibodies despite absence of systemic endotoxemia in patients with Crohn's disease.

Kruis W, Schussler P, Weinzierl M, Galanos C, Eisenburg J Dig Dis Sci. 1984; 29(6):502-7.

PMID: 6144475 DOI: 10.1007/BF01296269.

Absence of complement fixing antibodies against lipopolysaccharides from Escherichia coli in a subgroup of patients with Crohn's disease.

Zeitz M, Hope U, Wust B, Galanos C, Moller B, Lawley T Gut. 1987; 28(11):1460-6.

PMID: 3322954 PMC: 1433671. DOI: 10.1136/gut.28.11.1460.

Immune status in Crohn's disease. 3. Peripheral blood B lymphocytes, enumerated by means of F(ab)2-antibody fragments, Null and T lymphocytes.

Auer I, Gotz S, Ziemer E, Malchow H, Ehms H Gut. 1979; 20(4):261-8.

PMID: 312753 PMC: 1412387. DOI: 10.1136/gut.20.4.261.

References

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