Article: Some peculiar synaptic complexes in the first visual ganglion of the fly, Musca domestica

In the lamina ganglionaris, the first optic ganglion of the fly, the inventory of cell types as well as the patterns of their connections are well known from light microscopic investigations. Even the synaptic contacts are known with relative completeness. However, the structural details visible on electron micrographs are very difficult to interpret in functional terms. This paper concentrates on two aspects: 1) the synaptic complex between a retinula cell axon and four postsynaptic elements, arranged in a constant elongated array (it is suggested that all synapses in which the retinula cell is presynaptic are of this kind), and 2) the "gnarl" complex in which a presynaptic specialization in one neuron is separated from another neuron by a complicated glial invagination. The participation of glia at postsynaptic sites seems to be quite common in this ganglion. Occasionally it seems that a glia cell is the only postsynaptic partner facing a presynaptic specialization within a neuron.

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References

1.

DROCHMANS P . [Morphology of glycogen. Electron microscopic study of the negative stains of particulate glycogen]. J Ultrastruct Res. 1962; 6:141-63. DOI: 10.1016/s0022-5320(62)90050-3. View

2.

COLONNIER M . THE TANGENTIAL ORGANIZATION OF THE VISUAL CORTEX. J Anat. 1964; 98:327-44. PMC: 1261360. View

3.

Rosenbluth J . Subsurface cisterns and their relationship to the neuronal plasma membrane. J Cell Biol. 1962; 13:405-21. PMC: 2106078. DOI: 10.1083/jcb.13.3.405. View

4.

Strausfeld N . The optic lobes of Diptera. Philos Trans R Soc Lond B Biol Sci. 2012; 258(820):135-223. DOI: 10.1098/rstb.1970.0033. View

5.

TRUJILLO-CENOZ O, Melamed J . Light and electronmicroscope study of one of the systems of centrifugal fibers found in the lamina of muscoid flies. Z Zellforsch Mikrosk Anat. 1970; 110(3):336-49. DOI: 10.1007/BF00321146. View

6.

Braitenberg V . [Order and orientation of elements in the visual system of the fly]. Kybernetik. 1970; 7(6):235-42. View

7.

Campos-Ortega J, Strausfeld N . Synaptic connections of intrinsic cells and basket arborizations in the external plexiform layer of the fly's eye. Brain Res. 1973; 59:119-36. DOI: 10.1016/0006-8993(73)90255-2. View

8.

Strausfeld N, Campos-Ortega J . The L4 monopolar neurone: a substrate for lateral interaction in the visual system of the fly Musca domestica (L.). Brain Res. 1973; 59:97-117. DOI: 10.1016/0006-8993(73)90254-0. View

9.

Boschek C . On the fine structure of the peripheral retina and lamina ganglionaris of the fly, Musca domestica. Z Zellforsch Mikrosk Anat. 1971; 118(3):369-409. DOI: 10.1007/BF00331193. View

10.

TRUJILLO-CENOZ O . Some aspects of the structural organization of the medulla in muscoid flies. J Ultrastruct Res. 1969; 27(5):533-53. DOI: 10.1016/s0022-5320(69)80048-1. View

11.

TRUJILLO-CENOZ O . Some aspects of the structural organization of the intermediate retina of dipterans. J Ultrastruct Res. 1965; 13(1):1-33. DOI: 10.1016/s0022-5320(65)80086-7. View

12.

Braitenberg V . Patterns of projection in the visual system of the fly. I. Retina-lamina projections. Exp Brain Res. 1967; 3(3):271-98. DOI: 10.1007/BF00235589. View

Some Peculiar Synaptic Complexes in the First Visual Ganglion of the Fly, Musca Domestica