Mutators and Long-term Molecular Evolution of Pathogenic Escherichia Coli O157:H7

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 1998 Dec 29

PMID 9866737

Citations 7

Authors

T S Whittam

S D Reid

R K Selander

Affiliations

Soon will be listed here.

Abstract

It has been proposed that an increased mutation rate (indicated by the frequency of hypermutable isolates) has facilitated the emergence of Escherichia coli O157:H7. Analysis of the divergence of 12 genes shows no evidence that the pathogen has undergone an unusually high rate of mutation and molecular evolution.

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