Excess Mortality of Mental Disorder

Overview

Journal Br J Psychiatry

Publisher Cambridge University Press

Specialty Psychiatry

Date 1998 Dec 16

PMID 9850203

Citations 435

Authors

E C Harris

B Barraclough

Affiliations

Soon will be listed here.

Abstract

Background: We describe the increased risk of premature death from natural and from unnatural causes for the common mental disorders.

Method: With a Medline search (1966-1995) we found 152 English language reports on the mortality of mental disorder which met our inclusion criteria. From these reports, covering 27 mental disorder categories and eight treatment categories, we calculated standardised mortality ratios (SMRs) and 95% confidence intervals (CIs) for all causes of death, all natural causes and all unnatural causes; and for most, SMRs for suicide, other violent causes and specific natural causes.

Results: Highest risks of premature death, from both natural and unnatural causes, are for substance abuse and eating disorders. Risk of death from unnatural causes is especially high for the functional disorders, particularly schizophrenia and major depression. Deaths from natural causes are markedly increased for organic mental disorders, mental retardation and epilepsy.

Conclusion: All mental disorders have an increased risk of premature death.

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