Lymphocytic Infundibuloneurohypophysitis Presenting As Diabetes Insipidus in a Man

Overview

Journal J Endocrinol Invest

Publisher Springer

Specialty Endocrinology

Date 1998 Nov 5

PMID 9801996

Citations 1

Authors

N Kamel

S D Ilgin

D Corapcioglu

H Deda

S Gullu

Affiliations

Soon will be listed here.

Abstract

We report a patient with diabetes insipidus, whose sella magnetic resonance imaging revealed a normal hypophysis with a focal nodular thickening of the infundibulum and lack of hyper-intense signal of the normal neurohypophysis. The histopathologic examination of the lesion showed a lymphoplasmacytic, predominantly lymphocytic, infiltration. A diagnosis of lymphocytic infundibuloneurohypophysitis was made, by the exclusion of other infiltrative, granulomatous diseases.

Citing Articles

The Pituitary Gland: An Infrequent but Multifaceted Contributor to Death.

Wang A, Gill J Acad Forensic Pathol. 2019; 6(2):206-216.

PMID: 31239893 PMC: 6507013. DOI: 10.23907/2016.023.

References

Imura H, Nakao K, Shimatsu A, Ogawa Y, Sando T, Fujisawa I . Lymphocytic infundibuloneurohypophysitis as a cause of central diabetes insipidus. N Engl J Med. 1993; 329(10):683-9. DOI: 10.1056/NEJM199309023291002. View

Guay A, Agnello V, Tronic B, Gresham D, Freidberg S . Lymphocytic hypophysitis in a man. J Clin Endocrinol Metab. 1987; 64(3):631-4. DOI: 10.1210/jcem-64-3-631. View

Greger N, Kirkland R, Clayton G, Kirkland J . Central diabetes insipidus. 22 years' experience. Am J Dis Child. 1986; 140(6):551-4. DOI: 10.1001/archpedi.1986.02140200061028. View

Thodou E, Asa S, Kontogeorgos G, Kovacs K, Horvath E, Ezzat S . Clinical case seminar: lymphocytic hypophysitis: clinicopathological findings. J Clin Endocrinol Metab. 1995; 80(8):2302-11. DOI: 10.1210/jcem.80.8.7629223. View

Cosman F, Post K, Holub D, Wardlaw S . Lymphocytic hypophysitis. Report of 3 new cases and review of the literature. Medicine (Baltimore). 1989; 68(4):240-56. DOI: 10.1097/00005792-198907000-00006. View