Solid-phase Microtiter Radioimmunoassay for Detection of the Norwalk Strain of Acute Nonbacterial, Epidemic Gastroenteritis Virus and Its Antibodies

Overview

Journal J Med Virol

Specialty Microbiology

Date 1978 Jan 1

PMID 97365

Citations 53

Authors

H B Greenberg

R G Wyatt

J Valdesuso

A R Kalica

W T London

R M Chanock

A Z Kapikian

Affiliations

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Abstract

The development of microtiter solid-phase radioimmunoassays for the detection of Norwalk antigen and its antibody is described. The tests are simple to perform and are sensitive and specific. The test for antigen can be used on crude stool filtrates and suspensions. Both tests are at least as sensitive as immune electron microscopy and more sensitive than immune adherence assay.

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