A Case of Hemolytic Uremic Syndrome Associated with Epstein-Barr Virus Infection

Overview

Journal Korean J Intern Med

Specialty General Medicine

Date 1998 Sep 15

PMID 9735670

Citations 4

Authors

M H Lee

K S Cho

K W Kahng

C M Kang

Affiliations

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Abstract

The precise etiology of hemolytic uremic syndrome (HUS) is unknown. However, it has been associated with bacterial (Shigella, Salmonella, E. coli, S. pneumoniae), Bartonella, and viral (coxsackie, ECHO, influenza, varicella. Epstein-Barr) infections and with endotoxemia. Recently, we experienced a case of HUS in a 16-year-old boy who was in the acute phase of an Epstein-Barr virus (EBV) infection. He had typical manifestations of HUS and EBV infection. He also transiently presented disseminated intravascular coagulation. His renal dysfunction recovered by supportive care, including hemodialysis, plasmapheresis, antihypertensive medication and aspirin. We present this case with a review of the literature as the second report of HUS associated with EBV infection.

Citing Articles

Occurrence of atypical HUS associated with influenza B.

van Hoeve K, Vandermeulen C, Van Ranst M, Levtchenko E, van den Heuvel L, Mekahli D Eur J Pediatr. 2017; 176(4):449-454.

PMID: 28110418 DOI: 10.1007/s00431-017-2856-5.

Severe thrombocytopenia and recurrent epistaxis associated with primary Epstein-Barr virus infection.

Tilden W, Valliani S BMJ Case Rep. 2015; 2015.

PMID: 25858924 PMC: 4401940. DOI: 10.1136/bcr-2014-208018.

Hemolytic uremic syndrome associated with Epstein-Barr virus infection.

Watanabe T Pediatr Nephrol. 2004; 19(5):569.

PMID: 14997372 DOI: 10.1007/s00467-004-1416-1.

Hemolytic uremic syndrome linked to infectious mononucleosis.

Simonetti G, Dumont-Dos Santos K, Pachlopnik J, Ramelli G, Bianchetti M Pediatr Nephrol. 2003; 18(11):1193-4.

PMID: 13680327 DOI: 10.1007/s00467-003-1265-3.

References

Shashaty G, ATAMER M . Hemolytic uremic syndrome associated with infectious mononucleosis. Am J Dis Child. 1974; 127(5):720-2. DOI: 10.1001/archpedi.1974.02110240106016. View

Lee S, Kjellstrand C . Renal disease in infectious mononucleosis. Clin Nephrol. 1978; 9(6):236-40. View

Shurin S . Infectious mononucleosis. Pediatr Clin North Am. 1979; 26(2):315-26. DOI: 10.1016/s0031-3955(16)33708-7. View

Mccabe J, Duckett S, Kaplan P . Epstein-Barr virus infection complicated by acute rhabdomyolysis. Am J Emerg Med. 1988; 6(5):453-5. DOI: 10.1016/0735-6757(88)90244-6. View

Badami K, Srivastava R, Kumar R, Saraya A . Disseminated intravascular coagulation in post-dysenteric haemolytic uraemic syndrome. Acta Paediatr Scand. 1987; 76(6):919-22. DOI: 10.1111/j.1651-2227.1987.tb17264.x. View