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Effect of Sulfated and Non-sulfated Gastrin and Octapeptide-cholecystokinin on Cat Gall Bladder in Vitro

Overview
Journal Experientia
Specialty Science
Date 1976 Sep 15
PMID 971753
Citations 6
Authors
J R Chowdhury
J M Berkowitz
M Praissman
J W Fara
Affiliations
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Abstract

This study demonstrates that for the isolated cat gall bladder a smaller molar dose of the sulfated form of OP-CCK and gastrin is required to produce contraction as compared to the respective non-sulfated forms. For OP the D50 for the sulfated form versus the non-sulfated form was 1.94. For gastrin it was 1.10.

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References
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Chowdhury J, Berkowitz J, Praissman M, Fara J . Interaction between octapeptide-cholecystokinin, gastrin, and secretin on cat gallbladder in vitro. Am J Physiol. 1975; 229(5):1311-5. DOI: 10.1152/ajplegacy.1975.229.5.1311. View