Cell Adhesion Molecules in Cord Blood Hematopoietic Progenitors

Overview

Journal Bone Marrow Transplant

Specialty General Surgery

Date 1998 Aug 26

PMID 9715892

Citations 1

Authors

F Timeus

N Crescenzio

D Marranca

M Dallaglio

L Fazio

M Di Marco

P Saracco

M Ricotti

V Gabutti

Affiliations

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Abstract

We investigated the expression of different cell adhesion molecules on cord blood (CB) and bone marrow (BM) CD34+/CD38+ and CD34+/CD38- cells. CD11a and CD62L were more expressed in CB than in BM CD34+/CD38- subset, suggesting a possible advantage in homing and engraftment. A short exposure to various cytokines increased CD62L expression only in the more differentiated CB and BM CD34+/CD38+ cells.

Citing Articles

Hematopoietic capability of CD34+ cord blood cells: a comparison with CD34+ adult bone marrow cells.

Ueda T, Yoshida M, Yoshino H, Kobayashi K, Kawahata M, Ebihara Y Int J Hematol. 2001; 73(4):457-462.

PMID: 11503959 DOI: 10.1007/BF02994007.