Structure and Function of Molybdopterin Containing Enzymes

Overview

Journal Prog Biophys Mol Biol

Specialties Biophysics
Molecular Biology

Date 1997 Jan 1

PMID 9652170

Citations 14

Authors

M J Romao

J Knablein

R Huber

J J Moura

Affiliations

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Abstract

Molybdopterin containing enzymes are present in a wide range of living systems and have been known for several decades. However, only in the past two years have the first crystal structures been reported for this type of enzyme. This has represented a major breakthrough in this field. The enzymes share common structural features, but reveal different polypeptide folding topologies. In this review we give an account of the related spectroscopic information and the crystallographic results, with emphasis on structure-function studies.

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