Evaluation of Hemolysis in Patients with Prosthetic Heart Valves

Overview

Journal Clin Cardiol

Specialty Cardiology & Vascular Diseases

Date 1998 Jun 19

PMID 9631266

Citations 17

Authors

R Maraj

L E Jacobs

A Ioli

M N Kotler

Affiliations

Soon will be listed here.

Abstract

The primary mechanism and most common cause of hemolytic disease in patients with prosthetic heart valves are mechanical trauma to red blood cells and paraprosthetic valvular regurgitation, respectively. Presenting features in patients with this condition include anemia, congestive heart failure, fatigue, jaundice, dark urine, and a regurgitant murmur. Various laboratory studies can be utilized to diagnose hemolytic anemia and to assess the severity of hemolysis. Transthoracic echocardiography, transesophageal echocardiography, and Doppler studies including color Doppler are useful imaging methods to assess valve function. Treatment is usually medical (oral iron); however, in patients with paravalvular regurgitation, surgery is often required to correct the anemia.

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