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Mechanisms of Leucocyte Migration Inhibition by Breast Tumour Cell Fractions

Overview
Journal Br J Cancer
Specialty Oncology
Date 1976 Jul 1
PMID 952712
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Abstract

Leucocyte migration inhibition by autologous breast tumour cell fractions was mediated by a soluble factor synthesized and released by mononuclear leucocytes and active against migrating granulocytes. This mechanism is similar to that previously described in respect to cell-mediated sensitivity to microbial antigens. Alternative mechanisms involving directly reactive granulocytes or cytophilic antibodies were rarely operative in the migration tests.

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