» Articles » PMID: 9458618

The Effect of Race on Incidence and Clinical Course in Systemic Lupus Erythematosus: The Hopkins Lupus Cohort

Overview
Specialty General Medicine
Date 1998 Feb 12
PMID 9458618
Citations 10
Authors
Affiliations
Soon will be listed here.
Abstract

Systemic lupus erythematosus, a chronic autoimmune disease of young women, has a higher incidence and prevalence in African Americans. The Hopkins Lupus Cohort, a prospective longitudinal study of SLE outcomes, has shown that race is a major predictor of clinical manifestations, laboratory and serologic tests, and disease-related morbidity. The effect of race on musculoskeletal morbidity remains even after adjustment for education, insurance status, and smoking.

Citing Articles

The genomics of autoimmune disease in the era of genome-wide association studies and beyond.

Lessard C, Ice J, Adrianto I, Wiley G, Kelly J, Gaffney P Autoimmun Rev. 2011; 11(4):267-75.

PMID: 22001415 PMC: 3288956. DOI: 10.1016/j.autrev.2011.10.003.


Time to renal disease and end-stage renal disease in PROFILE: a multiethnic lupus cohort.

Alarcon G, McGwin Jr G, Petri M, Ramsey-Goldman R, Fessler B, Vila L PLoS Med. 2006; 3(10):e396.

PMID: 17076550 PMC: 1626549. DOI: 10.1371/journal.pmed.0030396.


Genetic linkage of systemic lupus erythematosus to 13q32 in African American families with affected male members.

Xing C, Gray-McGuire C, Kelly J, Garriott P, Bukulmez H, Harley J Hum Genet. 2005; 118(3-4):309-21.

PMID: 16189706 DOI: 10.1007/s00439-005-0061-5.


SLEN2 (2q34-35) and SLEN1 (10q22.3) replication in systemic lupus erythematosus stratified by nephritis.

Quintero-Del-Rio A, Kelly J, Garriott C, Hutchings D, Frank S, Aston C Am J Hum Genet. 2004; 75(2):346-8.

PMID: 15307049 PMC: 1216070. DOI: 10.1086/422460.


Linkage at 12q24 with systemic lupus erythematosus (SLE) is established and confirmed in Hispanic and European American families.

Nath S, Quintero-Del-Rio A, Kilpatrick J, Feo L, Ballesteros M, Harley J Am J Hum Genet. 2003; 74(1):73-82.

PMID: 14658095 PMC: 1181914. DOI: 10.1086/380913.