[Animal Models of Osteoporosis]
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The authors review the literature regarding the animal models of osteoporosis in two main groups: The resorption-dominant models (oovariectomy, orchiectomy, limbs imobilization, calcium restriction and use of hormonies) and another group, the formation-deficit models (senil rats, SAM mouse, glucocorticoid administration or limbs imobilization.
Sosic-Jurjevic B, Ajdzanovic V, Filipovic B, Severs W, Milosevic V Front Endocrinol (Lausanne). 2019; 10:688.
PMID: 31681166 PMC: 6798150. DOI: 10.3389/fendo.2019.00688.
EFFECTS OF ZOLEDRONIC ACID ON OOFORECTOMIZED RATS' TIBIAE: A PROSPECTIVE AND RANDOMIZED STUDY.
Alves Pereira F, Dutra R, Reis Olimpio T, Muller S, Palacio E Rev Bras Ortop. 2016; 44(1):61-8.
PMID: 26998455 PMC: 4783609. DOI: 10.1016/S2255-4971(15)30051-3.