Pulmonary Blastoma
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Pulmonary blastoma is now accepted as a distinctive neoplasm. It remains rare, and only 28 cases have been reliably recorded. A further two cases are now reported, and the previous literature is reviewed. There are no specific clinical or radiological features of pulmonary blastoma. The presentation can be that of any other pulmonary tumour although a peripheral situation is usual and a large size is often attained before detection. Pulmonary blastoma is a mixed tumour with malignant epithelial and connective tissue components with a distinctive resemblance to fetal lung. The treatment of choice is surgical excision but the overall prognosis is poor. It is doubtful whether the tumour has a true blastomatous origin.
Pleuropulmonary blastoma in a 3-year-old child with persistent fever: a case report.
Yue R, Ma G, Mao L, Ni Q Front Pediatr. 2025; 13:1534277.
PMID: 40046857 PMC: 11880607. DOI: 10.3389/fped.2025.1534277.
Lewis J, Petty W, Urbanic J, Bernstein E, Ahmed T Cureus. 2019; 10(11):e3586.
PMID: 30656089 PMC: 6333266. DOI: 10.7759/cureus.3586.
Comprehensive review of fetal adenocarcinoma of the lung.
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PMID: 30197546 PMC: 6112786. DOI: 10.2147/LCTT.S137410.
The Radiologic and Pathologic Diagnosis of Biphasic Pulmonary Blastoma.
Nemeh F, Kuo A, Ross J, Restrepo C J Radiol Case Rep. 2018; 11(9):10-21.
PMID: 29299105 PMC: 5743140. DOI: 10.3941/jrcr.v11i9.3153.
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PMID: 6287397 DOI: 10.1007/BF00971804.