» Articles » PMID: 9397684

Inositol Lipid 5-phosphatases--traffic Signals and Signal Traffic

Overview
Specialty Biochemistry
Date 1997 Dec 16
PMID 9397684
Citations 15
Authors
Affiliations
Soon will be listed here.
Abstract

Several novel phosphoinositide 5-phosphatases have been identified and characterised, revealing a growing family of regulators of inositol lipid dependent processes. The features of these proteins, their likely partners and their involvement in signal transduction and membrane traffic is discussed.

Citing Articles

Development of mutation-selective LRRK2 kinase inhibitors as precision medicine for Parkinson's disease and other diseases for which carriers are at increased risk.

Lesniak R, Nichols R, Montine T Front Neurol. 2022; 13:1016040.

PMID: 36388213 PMC: 9643380. DOI: 10.3389/fneur.2022.1016040.


Phosphoinositide phosphatases in a network of signalling reactions.

Blero D, Payrastre B, Schurmans S, Erneux C Pflugers Arch. 2007; 455(1):31-44.

PMID: 17605038 DOI: 10.1007/s00424-007-0304-5.


A novel mode of action for a microbial-derived immunotoxin: the cytolethal distending toxin subunit B exhibits phosphatidylinositol 3,4,5-triphosphate phosphatase activity.

Shenker B, Dlakic M, Walker L, Besack D, Jaffe E, Labelle E J Immunol. 2007; 178(8):5099-108.

PMID: 17404292 PMC: 4472023. DOI: 10.4049/jimmunol.178.8.5099.


Platelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through Akt.

Cartel N, Wang J, Post M Biochem J. 2002; 363(Pt 1):19-28.

PMID: 11903042 PMC: 1222446. DOI: 10.1042/0264-6021:3630019.


SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreading.

Prasad N, Topping R, Decker S Mol Cell Biol. 2001; 21(4):1416-28.

PMID: 11158326 PMC: 99593. DOI: 10.1128/MCB.21.4.1416-1428.2001.