The Glycoprotein IIb/IIIa Platelet Receptor Blocker Tirofiban, but Not Heparin, Counteracts Platelet Aggregation in Unstable Angina Pectoris

In this study, despite concomitant aspirin treatment, tirofiban, but not heparin, reduced platelet aggregation in patients with acute myocardial ischemia. Platelet aggregation was determined with 2 independent methods, filtragometry and whole blood aggregometry.