» Articles » PMID: 937615

Irritating Effects on Man of Air Pollution Due to Cigarette Smoke

Overview
Specialty Public Health
Date 1976 Jul 1
PMID 937615
Citations 15
Authors
Affiliations
Soon will be listed here.
Abstract

Sixty subjects were exposed to cigaretts smoke produced by a smoking machine in a climatic chamber. The irritating effects were recorded by questionnaire and related to concentrations of CO, formaldehyde, and acroleine. The eyes are most sensitive to these irritants, followed by the nose. Annoyance about air quality, and the desire to open the window or to leave the room proved to be other useful measures of sensitivity. With smoke produced by 10 cigarettes/30 m3 acroleine reaches 0.1 ppm, the threshold limit value for industries; simultaneously, CO and formaldehyde exceed the clean air standards for outdoor air. At this exposure level. 9 per cent of the subjects show a strong or very strong eye irritation, while 78 per cent "wish to leave the room." The most important of the measured irritants seems to be acroleine.

Citing Articles

Proteomic identification of moesin upon exposure to acrolein.

Lee P, Kim B, Lee S, Leikauf G, Jang A Proteome Sci. 2018; 16:2.

PMID: 29375273 PMC: 5773073. DOI: 10.1186/s12953-017-0130-4.


Acute effects of acrolein in human volunteers during controlled exposure.

Dwivedi A, Johanson G, Lorentzen J, Palmberg L, Sjogren B, Ernstgard L Inhal Toxicol. 2015; 27(14):810-21.

PMID: 26635308 PMC: 4732413. DOI: 10.3109/08958378.2015.1115567.


Respiratory Effects of Passive Smoking: Discovering the effects of environmental cigarette smoke.

Shephard R Can Fam Physician. 2011; 37:961-7.

PMID: 21229076 PMC: 2145654.


Endothelial dysfunction and claudin 5 regulation during acrolein-induced lung injury.

Jang A, Concel V, Bein K, Brant K, Liu S, Pope-Varsalona H Am J Respir Cell Mol Biol. 2010; 44(4):483-90.

PMID: 20525806 PMC: 3095921. DOI: 10.1165/rcmb.2009-0391OC.


Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.

Deshmukh H, McLachlan A, Atkinson J, Hardie W, Korfhagen T, Dietsch M Am J Respir Crit Care Med. 2009; 180(9):834-45.

PMID: 19661247 PMC: 2773913. DOI: 10.1164/rccm.200903-0328OC.


References
1.
Anderson G, DALHAMN T . [The risks to health of passive smoking]. Lakartidningen. 1973; 70(33):2833-6. View

2.
Harke H, Baars A, Frahm B, Peters H, Schultz C . [Passive smoking. Concentrations of smoke constituents in the air of large and small rooms as a function of number of cigarettes smoked and time]. Int Arch Arbeitsmed. 1972; 29(4):323-39. View

3.
Savel H . Clinical hypersensitivity to cigarette smoke. Arch Environ Health. 1970; 21(2):146-8. DOI: 10.1080/00039896.1970.10667212. View

4.
SPEER F . Tobacco and the nonsmoker. A study of subjective symptoms. Arch Environ Health. 1968; 16(3):443-6. DOI: 10.1080/00039896.1968.10665084. View

5.
Johansson C, RONGE H . [Influence of climate on the odor and irritant effect of tobacco smoke. Preliminary report]. Nord Hyg Tidskr. 1966; 47(1):33-9. View