» Articles » PMID: 9344057

A Male with Fetal Valproate Syndrome and Autism

Overview
Date 1997 Oct 31
PMID 9344057
Citations 46
Authors
Affiliations
Soon will be listed here.
Abstract

Fetal valproate syndrome (FVS) is characterized by minor craniofacial anomalies, major organ malformations, and developmental delay. We report on a patient who has a clinical phenotype compatible with both FVS and autism. The presence of an autistic disorder in a previously reported case of FVS and similar findings in our patient suggest that a relation between this known teratogen and autism may exist.

Citing Articles

Local and long-range input balance: A framework for investigating frontal cognitive circuit maturation in health and disease.

Allen S, Morishita H Sci Adv. 2024; 10(38):eadh3920.

PMID: 39292771 PMC: 11409946. DOI: 10.1126/sciadv.adh3920.


Gestational valproic acid exposure enhances facial stimulation-evoked cerebellar mossy fiber-granule cell transmission via GluN2A subunit-containing NMDA receptor in offspring mice.

Yuan Y, Liu Y, Zhang J, Bing Y, Chen C, Li G Transl Psychiatry. 2024; 14(1):272.

PMID: 38961057 PMC: 11222518. DOI: 10.1038/s41398-024-02990-0.


Valproic Acid in Pregnancy Revisited: Neurobehavioral, Biochemical and Molecular Changes Affecting the Embryo and Fetus in Humans and in Animals: A Narrative Review.

Ornoy A, Echefu B, Becker M Int J Mol Sci. 2024; 25(1).

PMID: 38203562 PMC: 10779436. DOI: 10.3390/ijms25010390.


Three Decades of Valproate: A Current Model for Studying Autism Spectrum Disorder.

Zarate-Lopez D, Torres-Chavez A, Galvez-Contreras A, Gonzalez-Perez O Curr Neuropharmacol. 2023; 22(2):260-289.

PMID: 37873949 PMC: 10788883. DOI: 10.2174/1570159X22666231003121513.


Transcriptome Analysis and Epigenetics Regulation in the Hippocampus and the Prefrontal Cortex of VPA-Induced Rat Model.

Chen L, Fu Q, Du Y, Jiang Z, Cheng Y Mol Neurobiol. 2023; 61(1):167-174.

PMID: 37592184 DOI: 10.1007/s12035-023-03560-z.