Immunogenetic Factors in Aetiology of Pre-eclampsia/eclampsia (gestosis)

Overview

Journal J Med Genet

Specialty Genetics

Date 1976 Jun 1

PMID 933120

Citations 1

Authors

J S Scott

D M Jenkins

Affiliations

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Abstract

The evidence that genetic and immunogenetic influences operate in the causation of pre-eclampsia/eclampsia (gestosis) is reviewed. The problems of definitive diagnosis are discussed along with the possibility of a multifactorial aetiology. The difficulties of differentiating trigger and effector mechanisms are also considered. It is concluded that there is evidence for a predisposition, probably genetic, operating in some cases, an immunogenetic mechanism in others, and chromosomal factors in a small group.

Citing Articles

Immunological factors in pre-eclampsia.

Br Med J. 1976; 2(6038):755.

PMID: 974591 PMC: 1688841.

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