Retroviral Techniques for Studying Organogenesis with a Focus on Heart Development

Overview

Journal Mol Cell Biochem

Publisher Springer

Specialty Biochemistry

Date 1997 Jul 1

PMID 9278229

Citations 2

Authors

J Hyer

T Mikawa

Affiliations

Soon will be listed here.

Abstract

The study of development has been revolutionized by the application of molecular techniques, which make it possible to identify factors involved in the developmental process. However, in order to correctly assess the contribution of these growth factors, transcription factors, receptors or signaling molecules, it is necessary to study them in the animal as a whole; it is not enough to conclude that they must be important based on their expression patterns.

Citing Articles

The expression of Wnt2b in the optic cup lip requires a border between the pigmented and nonpigmented epithelium.

Kitamoto J, Hyer J Mol Vis. 2010; 16:2701-17.

PMID: 21179237 PMC: 3002962.

FGF-mediated induction of ciliary body tissue in the chick eye.

Dias da Silva M, Tiffin N, Mima T, Mikawa T, Hyer J Dev Biol. 2007; 304(1):272-85.

PMID: 17275804 PMC: 1863121. DOI: 10.1016/j.ydbio.2006.12.033.

References

Cepko C, Ryder E, Austin C, Walsh C, Fekete D . Lineage analysis using retrovirus vectors. Methods Enzymol. 1993; 225:933-60. DOI: 10.1016/0076-6879(93)25059-b. View

Consigli S, Lyser K, Ver Pault C . Basic fibroblast growth factor in the chick embryo: immunolocalization to striated muscle cells and their precursors. J Cell Biol. 1989; 108(6):2459-66. PMC: 2115581. DOI: 10.1083/jcb.108.6.2459. View

Patstone G, Pasquale E, Maher P . Different members of the fibroblast growth factor receptor family are specific to distinct cell types in the developing chicken embryo. Dev Biol. 1993; 155(1):107-23. DOI: 10.1006/dbio.1993.1011. View

Lakso M, Sauer B, Mosinger Jr B, Lee E, Manning R, Yu S . Targeted oncogene activation by site-specific recombination in transgenic mice. Proc Natl Acad Sci U S A. 1992; 89(14):6232-6. PMC: 49474. DOI: 10.1073/pnas.89.14.6232. View

Mikawa T, Fischman D . Retroviral analysis of cardiac morphogenesis: discontinuous formation of coronary vessels. Proc Natl Acad Sci U S A. 1992; 89(20):9504-8. PMC: 50160. DOI: 10.1073/pnas.89.20.9504. View

Fekete D, Cepko C . Replication-competent retroviral vectors encoding alkaline phosphatase reveal spatial restriction of viral gene expression/transduction in the chick embryo. Mol Cell Biol. 1993; 13(4):2604-13. PMC: 359596. DOI: 10.1128/mcb.13.4.2604-2613.1993. View

Hasty P, Bradley A, Morris J, Edmondson D, Venuti J, Olson E . Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene. Nature. 1993; 364(6437):501-6. DOI: 10.1038/364501a0. View

Nabel E, Yang Z, Plautz G, Forough R, Zhan X, Haudenschild C . Recombinant fibroblast growth factor-1 promotes intimal hyperplasia and angiogenesis in arteries in vivo. Nature. 1993; 362(6423):844-6. DOI: 10.1038/362844a0. View

Ghattas I, Sanes J, Majors J . The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos. Mol Cell Biol. 1991; 11(12):5848-59. PMC: 361732. DOI: 10.1128/mcb.11.12.5848-5859.1991. View

10.

Sanes J . Analysing cell lineage with a recombinant retrovirus. Trends Neurosci. 1989; 12(1):21-8. DOI: 10.1016/0166-2236(89)90152-5. View

11.

Sanes J, Rubenstein J, Nicolas J . Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos. EMBO J. 1986; 5(12):3133-42. PMC: 1167303. DOI: 10.1002/j.1460-2075.1986.tb04620.x. View

12.

Nawrotzki R, Fischman D, Mikawa T . Antisense suppression of skeletal muscle myosin light chain-1 biosynthesis impairs myofibrillogenesis in cultured myotubes. J Muscle Res Cell Motil. 1995; 16(1):45-56. DOI: 10.1007/BF00125309. View

13.

Cepko C . Retrovirus vectors and their applications in neurobiology. Neuron. 1988; 1(5):345-53. DOI: 10.1016/0896-6273(88)90184-5. View

14.

Mima T, Ueno H, Fischman D, Williams L, Mikawa T . Fibroblast growth factor receptor is required for in vivo cardiac myocyte proliferation at early embryonic stages of heart development. Proc Natl Acad Sci U S A. 1995; 92(2):467-71. PMC: 42761. DOI: 10.1073/pnas.92.2.467. View

15.

Yamaguchi T, Harpal K, Henkemeyer M, Rossant J . fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev. 1994; 8(24):3032-44. DOI: 10.1101/gad.8.24.3032. View

16.

Dougherty J, Temin H . High mutation rate of a spleen necrosis virus-based retrovirus vector. Mol Cell Biol. 1986; 6(12):4387-95. PMC: 367221. DOI: 10.1128/mcb.6.12.4387-4395.1986. View

17.

Emerman M, Temin H . Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism. Cell. 1984; 39(3 Pt 2):449-67. View

18.

Mikawa T, Gourdie R . Pericardial mesoderm generates a population of coronary smooth muscle cells migrating into the heart along with ingrowth of the epicardial organ. Dev Biol. 1996; 174(2):221-32. DOI: 10.1006/dbio.1996.0068. View

19.

Petropoulos C, Hughes S . Replication-competent retrovirus vectors for the transfer and expression of gene cassettes in avian cells. J Virol. 1991; 65(7):3728-37. PMC: 241397. DOI: 10.1128/JVI.65.7.3728-3737.1991. View

20.

Amaya E, Musci T, Kirschner M . Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell. 1991; 66(2):257-70. DOI: 10.1016/0092-8674(91)90616-7. View