The Vertebrate Organizer: Structure and Molecules

Overview

Journal Trends Genet

Specialty Genetics

Date 1996 Dec 1

PMID 9257536

Citations 17

Authors

P Lemaire

L Kodjabachian

Affiliations

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Abstract

Since the identification of the first organizer gene, goosecoid, more than 15 organizer-specific genes have been characterized. Here, we present our current understanding of the roles of these molecules in amphibians fish and amniotes and show how there identification has confirmed Spemann's original proposition that the vertebrate organizer is subdivided into separate domains: the head, trunk and tail organizers.

Citing Articles

Cell lineage-guided mass spectrometry reveals increased energy metabolism and reactive oxygen species in the vertebrate organizer.

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The Organizer and Its Signaling in Embryonic Development.

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Functional Roles of FGF Signaling in Early Development of Vertebrate Embryos.

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Nuclear receptor NR4A is required for patterning at the ends of the planarian anterior-posterior axis.

Li D, McMann C, Reddien P Elife. 2019; 8.

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