Idiopathic Normal-pressure Hydrocephalus in Adults: Result of Shunting Correlated with Clinical Findings in 18 Patients and Review of the Literature

Overview

Journal Neurosurg Rev

Specialty Neurosurgery

Date 1997 Jan 1

PMID 9226668

Citations 5

Authors

R Caruso

L Cervoni

A M Vitale

M Salvati

Affiliations

Soon will be listed here.

Abstract

The authors describe their findings in a study aimed at identifying clinical-prognostic factors in treatment of idiopathic normal-pressure hydrocephalus. The study comprised 18 adult patients submitted to surgery for ventriculo-peritoneal shunting. The findings that emerged from this series of patients were compared with those reported for the 381 published cases. In our group of 18 patients, average age was 65 years and the average duration of clinical history was 47 months (median 18 months). Follow-up ranged from 3 to 5 years (median 4.2 years): 12 patients improved (9 completely) and 6 presented stable neurological deficits. The factors that had a statistically significant influence on outcome were a short clinical history (less than 6 months) (p = 0.05) and a clinical onset without dementia (p = 0.03). Patients with medium-grade preoperative ventricular enlargement always made a complete functional recovery after surgery (p = 0.2).

Citing Articles

Guidelines for Management of Idiopathic Normal Pressure Hydrocephalus (Third Edition): Endorsed by the Japanese Society of Normal Pressure Hydrocephalus.

Nakajima M, Yamada S, Miyajima M, Ishii K, Kuriyama N, Kazui H Neurol Med Chir (Tokyo). 2021; 61(2):63-97.

PMID: 33455998 PMC: 7905302. DOI: 10.2176/nmc.st.2020-0292.

Ventriculoperitoneal Shunt Outcomes of Normal Pressure Hydrocephalus: A Case Series of 116 Patients.

Wu E, El Ahmadieh T, Kafka B, Caruso J, Aoun S, Plitt A Cureus. 2019; 11(3):e4170.

PMID: 31093469 PMC: 6502283. DOI: 10.7759/cureus.4170.

High-Convexity Tightness Predicts the Shunt Response in Idiopathic Normal Pressure Hydrocephalus.

Narita W, Nishio Y, Baba T, Iizuka O, Ishihara T, Matsuda M AJNR Am J Neuroradiol. 2016; 37(10):1831-1837.

PMID: 27365329 PMC: 7960449. DOI: 10.3174/ajnr.A4838.

Clinical impact of the callosal angle in the diagnosis of idiopathic normal pressure hydrocephalus.

Ishii K, Kanda T, Harada A, Miyamoto N, Kawaguchi T, Shimada K Eur Radiol. 2008; 18(11):2678-83.

PMID: 18500524 DOI: 10.1007/s00330-008-1044-4.

[Gravity valves for idiopathic normal pressure hydrocephalus. A Prospective study of 60 patients].

Meier U Nervenarzt. 2004; 75(6):577-83.

PMID: 15156286 DOI: 10.1007/s00115-004-1695-6.

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