Anaerobic Infection in a Neonate. Early Detection by Gas Liquid Chromatography and Response to Metronidazole

Overview

Journal Arch Dis Child

Specialty Pediatrics

Date 1977 Sep 1

PMID 921328

Citations 4

Authors

S Rom

D Flynn

P Noone

Affiliations

Soon will be listed here.

Abstract

A case of presumptive anaerobic infection in a neonate is described to illustrate the use of gas-liquid chromatography in the early detection of these potentially serious pathogens. Metronidazole is suggested as a possibly useful antimicrobial agent in these infections.

Citing Articles

Intravenous metronidazole in the newborn.

Hall P, Kaye C, McIntosh N, Steele J Arch Dis Child. 1983; 58(7):529-31.

PMID: 6870333 PMC: 1628192. DOI: 10.1136/adc.58.7.529.

Disposition kinetics of metronidazole in children.

AMON I, Amon K, Scharp H, Franke G, Nagel F Eur J Clin Pharmacol. 1983; 24(1):113-9.

PMID: 6832193 DOI: 10.1007/BF00613937.

Antimicrobial drugs used in the management of anaerobic infections in children.

Brook I Drugs. 1983; 26(6):520-9.

PMID: 6360636 DOI: 10.2165/00003495-198326060-00004.

Metronidazole in anaerobic infections: a review of its activity, pharmacokinetics and therapeutic use.

Brogden R, Heel R, Speight T, Avery G Drugs. 1978; 16(5):387-417.

PMID: 363399 DOI: 10.2165/00003495-197816050-00002.

References

KISLAK J . The susceptibility of Bacteroides fragilis to 24 antibiotics. J Infect Dis. 1972; 125(3):295-9. DOI: 10.1093/infdis/125.3.295. View

Voogd C, van der Stel J, Jacobs J . The mutagenic action of nitroimidazoles. I. Metronidazole, nimorazole, dimetridazole and ronidazole. Mutat Res. 1974; 26(6):483-90. DOI: 10.1016/s0027-5107(74)80049-7. View

Tedesco F, Barton R, Alpers D . Clindamycin-associated colitis. A prospective study. Ann Intern Med. 1974; 81(4):429-33. DOI: 10.7326/0003-4819-81-4-429. View

Harrod J, Stevens D . Anaerobic infections in the newborn infant. J Pediatr. 1974; 85(3):399-402. DOI: 10.1016/s0022-3476(74)80129-0. View

Chow A, Leake R, Yamauchi T, Anthony B, Guze L . The significance of anaerobes in neonatal bacteremia: analysis of 23 cases and review of the literature. Pediatrics. 1974; 54(6):736-45. View