The Spread of Cancer in the Organism. Facts and Problems

Overview

Journal Naturwissenschaften

Specialty Science

Date 1977 Aug 1

PMID 917116

Authors

P STRAULI

Affiliations

Soon will be listed here.

Abstract

In this review, cancer is conceived as an alteration of the suface-monitored social behavior of cells. Apart from impaired growth controls, loss of residency (tissue affiliation) is the most important consequence of this homeostatic disorder. It results in local spread (penetration) which is initiated by locomotive and/or desctructive activities of the neoplastic cells. Access of cancer elements to the circulation possibly leads to distant spread (metastasis). Penetration and metastasis largely depend upon reactions of the organism, which are of an ill-understood, ambiguous nature favoring both the tumor and the host.

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