Effects of 8 Weeks' Endurance Training on Skeletal Muscle Metabolism in 56-70-year-old Sedentary Men

Overview

Journal Eur J Appl Physiol Occup Physiol

Specialty Occupational Medicine

Date 1977 Oct 31

PMID 913382

Citations 17

Authors

H Suominen

E Heikkinen

H Liesen

D Michel

W Hollmann

Affiliations

Soon will be listed here.

Abstract

The effects of 8 weeks' endurance training on muscle metabolism at rest and after a submaximal bicycle ergometer exercise were studied in 31 previously sedentary men, aged 56-70. Training consisted of 3-5 one hour exercise bouts per week including walking-jogging, swimming, gymnastics and ball games. The effects of training were similar to those previously reported for younger men. Mean maximal oxygen uptake increased (11%), as did the resting values for muscle glycogen concentration, the enzymes representing aerobic energy metabolism (malate dehydrogenase, succinate dehydrogenase), and also some of the anaerobic enzymes (creatine phosphokinase, lactate dehydrogenase). Lactate production during submaximal work decreased. The enzyme activities were lower following acute exercise both before and after training.

Citing Articles

Comparing the Impacts of Testosterone and Exercise on Lean Body Mass, Strength and Aerobic Fitness in Aging Men.

Green D, Chasland L, Yeap B, Naylor L Sports Med Open. 2024; 10(1):30.

PMID: 38563849 PMC: 10987448. DOI: 10.1186/s40798-024-00703-x.

Impact of Endurance and Resistance Training on Skeletal Muscle Glucose Metabolism in Older Adults.

Consitt L, Dudley C, Saxena G Nutrients. 2019; 11(11).

PMID: 31684154 PMC: 6893763. DOI: 10.3390/nu11112636.

The historical context and scientific legacy of John O. Holloszy.

Hagberg J, Coyle E, Baldwin K, Cartee G, Fontana L, Joyner M J Appl Physiol (1985). 2019; 127(2):277-305.

PMID: 30730811 PMC: 6732442. DOI: 10.1152/japplphysiol.00669.2018.

Effect of endurance and/or strength training on muscle fiber size, oxidative capacity, and capillarity in hemodialysis patients.

Lewis M, Fournier M, Wang H, Storer T, Casaburi R, Kopple J J Appl Physiol (1985). 2015; 119(8):865-71.

PMID: 26183484 PMC: 4610005. DOI: 10.1152/japplphysiol.01084.2014.

Differential Effect of Endurance Training on Mitochondrial Protein Damage, Degradation, and Acetylation in the Context of Aging.

Johnson M, Irving B, Lanza I, Vendelbo M, Konopka A, Robinson M J Gerontol A Biol Sci Med Sci. 2014; 70(11):1386-93.

PMID: 25504576 PMC: 4612384. DOI: 10.1093/gerona/glu221.

References

Klissouras V . Genetic limit of functional adaptability. Int Z Angew Physiol. 1972; 30(2):85-94. DOI: 10.1007/BF00704170. View

Saltin B . Metabolic fundamentals in exercise. Med Sci Sports. 1973; 5(3):137-46. View

Barnard R, Peter J . Effect of training and exhaustion on hexokinase activity of skeletal muscle. J Appl Physiol. 1969; 27(5):691-5. DOI: 10.1152/jappl.1969.27.5.691. View

Bjorntorp P, Fahlen M, Holm J, Schersten T, Szostak V . Determination of succinic oxidase activity in human skeletal muscle. Scand J Clin Lab Invest. 1970; 26(2):145-50. DOI: 10.3109/00365517009049226. View

Kiessling K, Pilstrom L, Bylund A, Saltin B, Piehl K . Enzyme activities and morphometry in skeletal muscle of middle-aged men after training. Scand J Clin Lab Invest. 1974; 33(1):63-9. DOI: 10.3109/00365517409114199. View

Saltin B, Wahren J, PERNOW B . Phosphagen and carbohydrate metabolism during exercise in trained middle-aged men. Scand J Clin Lab Invest. 1974; 33(1):71-7. DOI: 10.3109/00365517409114200. View

Gollnick P, Armstrong R, Saltin B, Saubert 4th C, Sembrowich W, Shepherd R . Effect of training on enzyme activity and fiber composition of human skeletal muscle. J Appl Physiol. 1973; 34(1):107-11. DOI: 10.1152/jappl.1973.34.1.107. View

Hyvarinen A, NIKKILA E . Specific determination of blood glucose with o-toluidine. Clin Chim Acta. 1962; 7:140-3. DOI: 10.1016/0009-8981(62)90133-x. View

Dohm G, Huston R, Askew E, Weiser P . Effects of exercise on activity of heart and muscle mitochondria. Am J Physiol. 1972; 223(4):783-7. DOI: 10.1152/ajplegacy.1972.223.4.783. View

10.

Karlsson J, Nordesjo L, Jorfeldt L, Saltin B . Muscle lactate, ATP, and CP levels during exercise after physical training in man. J Appl Physiol. 1972; 33(2):199-203. DOI: 10.1152/jappl.1972.33.2.199. View

11.

Adams G, deVries H . Physiological effects of an exercise training regimen upon women aged 52 to 79. J Gerontol. 1973; 28(1):50-5. DOI: 10.1093/geronj/28.1.50. View

12.

Karlsson J, Sjodin B, Thorstensson A, Hulten B, Frith K . LDH isozymes in skeletal muscles of endurance and strength trained athletes. Acta Physiol Scand. 1975; 93(2):150-6. DOI: 10.1111/j.1748-1716.1975.tb05803.x. View

13.

Ekblom B, Astrand P, Saltin B, Stenberg J, Wallstrom B . Effect of training on circulatory response to exercise. J Appl Physiol. 1968; 24(4):518-28. DOI: 10.1152/jappl.1968.24.4.518. View

14.

Green D, Mii S, KOHOUT P . Studies on the terminal electron transport system. I. Succinic dehydrogenase. J Biol Chem. 1955; 217(2):551-67. View

15.

Dohm G, Huston R, Askew E, Fleshood H . Effects of exercise, training, and diet on muscle citric acid cycle enzyme activity. Can J Biochem. 1973; 51(6):849-54. DOI: 10.1139/o73-105. View

16.

Saltin B, HARTLEY L, Kilbom A, ASTRAND I . Physical training in sedentary middle-aged and older men. II. Oxygen uptake, heart rate, and blood lactate concentration at submaximal and maximal exercise. Scand J Clin Lab Invest. 1969; 24(4):323-34. DOI: 10.3109/00365516909080169. View

17.

DE VRIES H . Physiological effects of an exercise training regimen upon men aged 52 to 88. J Gerontol. 1970; 25(4):325-36. DOI: 10.1093/geronj/25.4.325. View

18.

Suominen H, Heikkinen E . Enzyme activities in muscle and connective tissue of M. Vastus lateralis in habitually training and sedentary 33 to 70-year-old men. Eur J Appl Physiol Occup Physiol. 1975; 34(4):249-54. DOI: 10.1007/BF00999938. View

19.

Terjung R, Baldwin K, Mole P, KLINKERFUSS G, Holloszy J . Effect of running to exhaustion on skeletal muscle mitochondria: a biochemical study. Am J Physiol. 1972; 223(3):549-54. DOI: 10.1152/ajplegacy.1972.223.3.549. View

20.

Bostrom S, Fahlen M, Hjalmarson A, Johansson R . Activities of rat muscle enzymes after acute exercise. Acta Physiol Scand. 1974; 90(3):544-54. DOI: 10.1111/j.1748-1716.1974.tb05619.x. View