Tolerance to Marijuana: Heart Rate and Subjective "high"

Overview

Journal Clin Pharmacol Ther

Publisher Wiley

Specialty Pharmacology

Date 1977 Nov 1

PMID 913022

Citations 15

Authors

R Nowlan

S Cohen

Affiliations

Soon will be listed here.

Abstract

In a 94-day supervised study of 30 subjects smoking marijuana, with drug-free periods interspersed, mean heart rate and subjective "high" decreased over the smoking period. Light smokers had greater chronotrophic and subjective effects than heavy smokers, but both demonstrated evidence of tolerance. Cumulation and minor withdrawal effects were noted.

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