The Cost-effectiveness of the Nicotine Transdermal Patch for Smoking Cessation
Overview
Affiliations
Background: Smoking is the single most preventable cause of premature mortality in the United States. In 13 double-blind, controlled trials, the nicotine transdermal patch has been demonstrated to be an effective aid to quitting smoking, even after 6 months of follow-up. Because physicians and payers may consider the cost of the patch to be prohibitive, we examine the cost-effectiveness of the nicotine patch as an adjunct to brief physician counseling during routine office visits.
Methods: We estimate the effectiveness of both patch use with brief counseling and counseling alone from meta-analysis of clinical trials. Benefits are measured in terms of years of life gained by those who quit, discounted at 5%. Costs include physician time and patch prescriptions. The incremental cost-effectiveness is quantified as cost per additional year of life saved when patch plus counseling is compared with brief physician counseling alone.
Results: Depending on age, the average costs per year of life saved range from $965 to $1,585 for men and from $1,634 to $2,360 for women. Incremental costs per year of life saved range from $1,796 to $2,949 for men and from $3,040 to $4,391 for women.
Conclusion: The nicotine patch is cost-effective and less costly per year of life saved than other widely accepted medical practices. Physicians and third-party payers should recommend the nicotine patch to patients who wish to stop smoking.
Jonsdottir F, Snorradottir B, Gunnarsson S, Georgsdottir E, Sigurdsson S Pharmaceutics. 2022; 14(9).
PMID: 36145628 PMC: 9505649. DOI: 10.3390/pharmaceutics14091880.
Ibrahim M, Magzoub N, Maarup N J Clin Diagn Res. 2016; 10(2):LC11-5.
PMID: 27042488 PMC: 4800553. DOI: 10.7860/JCDR/2016/17641.7325.
Transdermal patches: the emerging mode of drug delivery system in psychiatry.
Isaac M, Holvey C Ther Adv Psychopharmacol. 2013; 2(6):255-63.
PMID: 23983984 PMC: 3736952. DOI: 10.1177/2045125312458311.
Smoking-cessation interventions in people living with HIV infection: a systematic review.
Moscou-Jackson G, Commodore-Mensah Y, Farley J, DiGiacomo M J Assoc Nurses AIDS Care. 2013; 25(1):32-45.
PMID: 23876816 PMC: 4105340. DOI: 10.1016/j.jana.2013.04.005.
Ruger J, Lazar C Annu Rev Public Health. 2012; 33:279-305.
PMID: 22224889 PMC: 3959760. DOI: 10.1146/annurev-publhealth-031811-124553.