Clinical Rationale of Genetic Testing in Dementia

Overview

Journal J Neurol Neurosurg Psychiatry

Publisher BMJ Publishing Group

Specialties Neurology
Neurosurgery
Psychiatry

Date 1997 Mar 1

PMID 9069471

Citations 1

Authors

G B Frisoni

M Trabucchi

Affiliations

Soon will be listed here.

Citing Articles

Signaling crossroads: the function of Raf kinase inhibitory protein in cancer, the central nervous system and reproduction.

Klysik J, Theroux S, Sedivy J, Moffit J, Boekelheide K Cell Signal. 2007; 20(1):1-9.

PMID: 17706925 PMC: 2231335. DOI: 10.1016/j.cellsig.2007.07.003.

References

Frisoni G, Bianchetti A, Trabucchi M, Govoni S . Diagnostic usefulness of apolipoprotein E epsilon 4 in the diagnosis of the dementias. J Neurol Neurosurg Psychiatry. 1996; 60(6):699-700. PMC: 1073967. DOI: 10.1136/jnnp.60.6.699-a. View

Mayeux R . Understanding Alzheimer's disease: expect more genes and other things. Ann Neurol. 1996; 39(6):689-90. DOI: 10.1002/ana.410390602. View

Pericak-Vance M, Johnson C, Rimmler J, Saunders A, Robinson L, DHondt E . Alzheimer's disease and apolipoprotein E-4 allele in an Amish population. Ann Neurol. 1996; 39(6):700-4. DOI: 10.1002/ana.410390605. View

Chung H, Roberts C, Greenberg S, Rebeck G, Christie R, Wallace R . Lack of association of trinucleotide repeat polymorphisms in very-low-density lipoprotein receptor gene with Alzheimer's disease. Ann Neurol. 1996; 39(6):800-3. DOI: 10.1002/ana.410390617. View

Saunders A, Hulette O, Welsh-Bohmer K, Schmechel D, Crain B, Burke J . Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease. Lancet. 1996; 348(9020):90-3. DOI: 10.1016/s0140-6736(96)01251-2. View

Hyman B, Gomez-Isla T, Briggs M, Chung H, Nichols S, KOHOUT F . Apolipoprotein E and cognitive change in an elderly population. Ann Neurol. 1996; 40(1):55-66. DOI: 10.1002/ana.410400111. View

Scheuner D, Eckman C, Jensen M, Song X, Citron M, Suzuki N . Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat Med. 1996; 2(8):864-70. DOI: 10.1038/nm0896-864. View

Tanzi R, Vaula G, Romano D, Mortilla M, Huang T, Tupler R . Assessment of amyloid beta-protein precursor gene mutations in a large set of familial and sporadic Alzheimer disease cases. Am J Hum Genet. 1992; 51(2):273-82. PMC: 1682666. View

Gerdes L, Klausen I, Sihm I, Faergeman O . Apolipoprotein E polymorphism in a Danish population compared to findings in 45 other study populations around the world. Genet Epidemiol. 1992; 9(3):155-67. DOI: 10.1002/gepi.1370090302. View

10.

Wiggins S, Whyte P, Huggins M, Adam S, Theilmann J, Bloch M . The psychological consequences of predictive testing for Huntington's disease. Canadian Collaborative Study of Predictive Testing. N Engl J Med. 1992; 327(20):1401-5. DOI: 10.1056/NEJM199211123272001. View

11.

Schellenberg G, Bird T, Wijsman E, Orr H, Anderson L, Nemens E . Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14. Science. 1992; 258(5082):668-71. DOI: 10.1126/science.1411576. View

12.

Strittmatter W, Saunders A, Schmechel D, Pericak-Vance M, Enghild J, Salvesen G . Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A. 1993; 90(5):1977-81. PMC: 46003. DOI: 10.1073/pnas.90.5.1977. View

13.

Cauley J, Eichner J, Kamboh M, Ferrell R, Kuller L . Apo E allele frequencies in younger (age 42-50) vs older (age 65-90) women. Genet Epidemiol. 1993; 10(1):27-34. DOI: 10.1002/gepi.1370100104. View

14.

Tournier-Lasserve E, Joutel A, Melki J, Weissenbach J, Lathrop G, Chabriat H . Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy maps to chromosome 19q12. Nat Genet. 1993; 3(3):256-9. DOI: 10.1038/ng0393-256. View

15.

Corder E, Saunders A, Strittmatter W, Schmechel D, Gaskell P, Small G . Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science. 1993; 261(5123):921-3. DOI: 10.1126/science.8346443. View

16.

Saunders A, Strittmatter W, Schmechel D, Pericak-Vance M, Joo S, Rosi B . Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology. 1993; 43(8):1467-72. DOI: 10.1212/wnl.43.8.1467. View

17.

Collinge J, Palmer M . Prion diseases in humans and their relevance to other neurodegenerative diseases. Dementia. 1993; 4(3-4):178-85. DOI: 10.1159/000107320. View

18.

Clark R, Goate A . Molecular genetics of Alzheimer's disease. Arch Neurol. 1993; 50(11):1164-72. DOI: 10.1001/archneur.1993.00540110044004. View

19.

Mayeux R, Stern Y, Ottman R, Tatemichi T, Tang M, Maestre G . The apolipoprotein epsilon 4 allele in patients with Alzheimer's disease. Ann Neurol. 1993; 34(5):752-4. DOI: 10.1002/ana.410340527. View

20.

St George-Hyslop P, McLachlan D, Tsuda T, Rogaev E, Karlinsky H, Lippa C . Alzheimer's disease and possible gene interaction. Science. 1994; 263(5146):537. DOI: 10.1126/science.8290965. View