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Orientation of Cell-surface Antigens in the Lipid Bilayer of Lymphocyte Plasma Membrane

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Journal Nature
Specialty Science
Date 1977 Sep 22
PMID 904685
Citations 38
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Abstract

Human HLA-A, B, C and Ia antigens were labelled by lactoperoxidase-catalysed iodination of the inner surface of lymphocyte plasma membrane and thus are transmembrane proteins. In contrast, membrane-bound human IgM and mouse IgM, IgD and Thy-1 antigen were not labelled on the inner membrane surface.

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