Transient Psychosis in a Girl with Epilepsy and Continuous Spikes and Waves During Slow Sleep (CSWS)

Overview

Journal Eur Child Adolesc Psychiatry

Specialties Pediatrics
Psychiatry

Date 1996 Dec 1

PMID 8989561

Authors

M Kyllerman

A Nyden

N Praquin

P Rasmussen

A K Wetterquist

A Hedstrom

Affiliations

Soon will be listed here.

Abstract

A normally developed and healthy 6-year-old girl suffered the onset of epilepsy with generalized tonic-clonic seizures and atypical absences. Initially the EEG showed epileptiform activity over the temporal and parietal regions, later there were episodes of bilateral synchronous spike-wave activity with a frequency of 1.5-2.5 Hz. After a few months, deterioration of cognitive and behavioural functions appeared and gradually increased with the development of a full-blown disintegrative psychosis that went on for several months. Sleep EEG recordings showed the characteristic abnormality described as continuous spikes and waves during slow sleep. Later there was a remarkable improvement of neuropsychiatric functions but a second outbreak of psychosis seems to have left the girl, who is now 9 years of age, with severe mental impairment.

References

Echenne B, Cheminal R, Rivier F, Negre C, Touchon J, Billiard M . Epileptic electroencephalographic abnormalities and developmental dysphasias: a study of 32 patients. Brain Dev. 1992; 14(4):216-25. DOI: 10.1016/s0387-7604(12)80233-6. View

Zatorre R . Memory loss following domoic acid intoxication from ingestion of toxic mussels. Can Dis Wkly Rep. 1990; 16 Suppl 1E:101-3; discussion 103-4. View

Gillberg C, Schaumann H . Epilepsy presenting as infantile autism? Two case studies. Neuropediatrics. 1983; 14(4):206-12. DOI: 10.1055/s-2008-1059580. View

Deonna T, Peter C, Ziegler A . Adult follow-up of the acquired aphasia-epilepsy syndrome in childhood. Report of 7 cases. Neuropediatrics. 1989; 20(3):132-8. DOI: 10.1055/s-2008-1071278. View

Nass R, Heier L, Walker R . Landau-Kleffner syndrome: temporal lobe tumor resection results in good outcome. Pediatr Neurol. 1993; 9(4):303-5. DOI: 10.1016/0887-8994(93)90069-o. View

Sutherland R, Hoesing J, Whishaw I . Domoic acid, an environmental toxin, produces hippocampal damage and severe memory impairment. Neurosci Lett. 1990; 120(2):221-3. DOI: 10.1016/0304-3940(90)90043-9. View

Boel M, Casaer P . Continuous spikes and waves during slow sleep: a 30 months follow-up study of neuropsychological recovery and EEG findings. Neuropediatrics. 1989; 20(3):176-80. DOI: 10.1055/s-2008-1071287. View

Patry G, Lyagoubi S, Tassinari C . Subclinical "electrical status epilepticus" induced by sleep in children. A clinical and electroencephalographic study of six cases. Arch Neurol. 1971; 24(3):242-52. DOI: 10.1001/archneur.1971.00480330070006. View

Teitelbaum J, Zatorre R, Carpenter S, Gendron D, Cashman N . Neurological sequelae of domoic acid intoxication. Can Dis Wkly Rep. 1990; 16 Suppl 1E:9-12. View

10.

DE NEGRI M . Developmental dysphasias, epilepsy, and Landau-Kleffner syndrome. Brain Dev. 1993; 15(4):319. DOI: 10.1016/0387-7604(93)90035-7. View

11.

Deonna T, Ziegler A, Innocenti G . Autistic regression in relation to limbic pathology and epilepsy: report of two cases. Dev Med Child Neurol. 1993; 35(2):166-76. DOI: 10.1111/j.1469-8749.1993.tb11619.x. View

12.

Steffenburg S . Neuropsychiatric assessment of children with autism: a population-based study. Dev Med Child Neurol. 1991; 33(6):495-511. DOI: 10.1111/j.1469-8749.1991.tb14915.x. View

13.

Bishop D . Age of onset and outcome in 'acquired aphasia with convulsive disorder' (Landau-Kleffner syndrome). Dev Med Child Neurol. 1985; 27(6):705-12. DOI: 10.1111/j.1469-8749.1985.tb03793.x. View

14.

Carpenter S . The human neuropathology of encephalopathic mussel toxin poisoning. Can Dis Wkly Rep. 1990; 16 Suppl 1E:73-4. View

15.

KELLERMANN K . Recurrent aphasia with subclinical bioelectric status epilepticus during sleep. Eur J Pediatr. 1978; 128(3):207-12. DOI: 10.1007/BF00444306. View

16.

Olsson I, Steffenburg S, Gillberg C . Epilepsy in autism and autisticlike conditions. A population-based study. Arch Neurol. 1988; 45(6):666-8. DOI: 10.1001/archneur.1988.00520300086024. View