Transport of Proteins in Eukaryotic Cells: More Questions Ahead

Overview

Journal Plant Mol Biol

Date 1996 Oct 1

PMID 8980481

Citations 10

Authors

D C Bassham

N V Raikhel

Affiliations

Soon will be listed here.

Abstract

Some newly synthesized proteins contain signals that direct their transport to their final location within or outside of the cell. Targeting signals are recognized by specific protein receptors located either in the cytoplasm or in the membrane of the target organelle. Specific membrane protein complexes are involved in insertion and translocation of polypeptides across the membranes. Often, additional targeting signals are required for a polypeptide to be further transported to its site of function. In this review, we will describe the trafficking of proteins to various cellular organelles (nucleus, chloroplasts, mitochondria, peroxisomes) with emphasis on transport to and through the secretory pathway.

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