Cutaneous Metastases from Pancreatic Cancer

Overview

Journal Int J Pancreatol

Specialty Gastroenterology

Date 1996 Oct 1

PMID 8968868

Citations 24

Authors

M Miyahara

Y Hamanaka

A Kawabata

Y Sato

A Tanaka

A Yamamoto

T Ueno

K Nishihara

T Suzuki

Affiliations

Soon will be listed here.

Abstract

Cutaneous metastases originating from pancreatic cancer are relatively rare. Five cases of metastatic pancreatic cancer to the skin are presented and discussed with a review of 17 previous case reports. In 20 cases, the cutaneous metastases were present prior to the diagnosis of pancreatic cancer. The most common site of cutaneous metastases originating from pancreatic cancer was the umbilicus. Although such cases are rare, it is important to note that metastatic lesions in the skin may be the first sign and one type of distant metastases originating from pancreatic cancer.

Citing Articles

Cutaneous Metastasis: A Rare Presentation of Pancreatic Adenocarcinoma.

Nichkaode P, Dwivedi D Cureus. 2024; 16(9):e69767.

PMID: 39429388 PMC: 11491125. DOI: 10.7759/cureus.69767.

Rare Solid Pancreatic Lesions on Cross-Sectional Imaging.

Veron Sanchez A, Santamaria Guinea N, Cayon Somacarrera S, Bennouna I, Pezzullo M, Antonietta Bali M Diagnostics (Basel). 2023; 13(16).

PMID: 37627978 PMC: 10453474. DOI: 10.3390/diagnostics13162719.

Metastatic Pancreatic Acinar Cell Carcinoma: An Unlikely Culprit.

Bashinskaya A, Kammerman J, Butson D, Moody P Cureus. 2023; 15(4):e38288.

PMID: 37255915 PMC: 10226385. DOI: 10.7759/cureus.38288.

Pancreatic Adenosquamous Carcinoma: A Rare Pathological Subtype of Pancreatic Cancer.

Xiong Q, Zhang Z, Xu Y, Zhu Q J Clin Med. 2022; 11(24).

PMID: 36556016 PMC: 9781288. DOI: 10.3390/jcm11247401.

Skin manifestations of pancreatic diseases.

Kunovsky L, Dite P, Brezinova E, Sedlakova L, Trna J, Jabandziev P Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2022; 166(4):353-358.

PMID: 35938387 DOI: 10.5507/bp.2022.035.

References

Weiland F, Carretta R . 67Ga-citrate accumulation in a Sister Mary Joseph nodule. Clin Nucl Med. 1978; 3(8):335-6. DOI: 10.1097/00003072-197808000-00011. View

Schwartz R . Cutaneous metastatic disease. J Am Acad Dermatol. 1995; 33(2 Pt 1):161-82; quiz 183-6. DOI: 10.1016/0190-9622(95)90231-7. View

Bordin G, WEITZNER S . Cutaneous metastases as a manifestation of internal carcinoma: diagnostic and prognostic significance. Am Surg. 1972; 38(11):629-34. View

Powell F, Cooper A, Massa M, Goellner J, Su W . Sister Mary Joseph's nodule: a clinical and histologic study. J Am Acad Dermatol. 1984; 10(4):610-5. DOI: 10.1016/s0190-9622(84)80265-0. View

Lookingbill D, Spangler N, Helm K . Cutaneous metastases in patients with metastatic carcinoma: a retrospective study of 4020 patients. J Am Acad Dermatol. 1993; 29(2 Pt 1):228-36. DOI: 10.1016/0190-9622(93)70173-q. View

Sironi M, Radice F, Taccagni G, Braga M, Zerbi M . Fine needle aspiration of a pancreatic oxyphilic carcinoma with pulmonary and subcutaneous metastases. Cytopathology. 1991; 2(6):303-9. DOI: 10.1111/j.1365-2303.1991.tb00505.x. View

Taniguchi S, Hisa T, Hamada T . Cutaneous metastases of pancreatic carcinoma with unusual clinical features. J Am Acad Dermatol. 1994; 31(5 Pt 2):877-80. DOI: 10.1016/s0190-9622(94)70250-0. View

Shvili D, Halevy S, SANDBANK M . Umbilical metastasis as the presenting sign of pancreatic adenocarcinoma. Cutis. 1983; 31(5):555-6, 558. View

Charoenkul V, DELCAMPO A, Derby A, Hodgson W, McELHINNEY A . Tumors of the umbilicus. Mt Sinai J Med. 1977; 44(2):257-62. View

10.

Chatterjee S, Bauer H . Umbilical metastasis from carcinoma of the pancreas. Arch Dermatol. 1980; 116(8):954-5. View

11.

EDELSTEIN J . Pancreatic carcinoma with unusual metastasis to the skin and subcutaneous tissue simulating cellulitis. N Engl J Med. 1950; 242(20):779-81. DOI: 10.1056/NEJM195005182422003. View

12.

Scarpa F, Dineen J, Boltax R . Visceral neoplasia presenting at the umbilicus. J Surg Oncol. 1979; 11(4):351-9. DOI: 10.1002/jso.2930110410. View

13.

Chakraborty A, Reddy A, GROSBERG S, Wapnick S . Pancreatic carcinoma with dissemination to umbilicus and skin. Arch Dermatol. 1977; 113(6):838-9. View

14.

CUBILLA A, Fitzgerald P . Pancreas cancer. I. Duct adenocarcinoma. A clinical-pathologic study of 380 patients. Pathol Annu. 1978; 13 Pt 1:241-89. View

15.

BARROW M . Metastatic tumors of the umbilicus. J Chronic Dis. 1966; 19(10):1113-7. DOI: 10.1016/0021-9681(66)90144-5. View

16.

Colin-Jones D, Copping R, Gibbs D, Sharr M . Malignant Zollinger-Ellison syndrome with gastrin-containing skin metastases. Lancet. 1969; 1(7593):492-4. DOI: 10.1016/s0140-6736(69)91591-8. View

17.

Horn J, FRED H, Lane M, HUDGINS P . UMBILICAL METASTASES. Arch Intern Med. 1964; 114:799-802. DOI: 10.1001/archinte.1964.03860120111012. View