Palliation of Malignant Dysphagia: an Alternative to Surgery

Overview

Journal Ann R Coll Surg Engl

Specialty General Surgery

Date 1996 Sep 1

PMID 8881732

Citations 5

Authors

R Mason

Affiliations

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Abstract

This paper presents the results of palliative treatment of 474 patients with malignant dysphagia. Laser produces good relief of symptoms but requires frequent repetition. Self-expanding metal stents provide one-off relief of dysphagia but do have complications. A randomised trial of laser versus covered and uncovered metal stents has demonstrated improved relief of dysphagia of stents over laser, but highlighted the problems at the cardia when stents are used. Chemotherapy in patients with advanced adenocarcinoma using epirubicin, cisplatin and 5-fluorouracil produces a response in two-thirds of cases, with relief of dysphagia and possible increase in survival. A treatment plan for palliation of patients with malignant dysphagia is presented.

Citing Articles

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Vieira de Brito R, Mancini M, Palumbo M, de Moraes L, Rodrigues G, Cervantes O Int J Mol Sci. 2022; 23(11).

PMID: 35682611 PMC: 9180481. DOI: 10.3390/ijms23115934.

Intratumoural injection of absolute alcohol in carcinoma of gastroesophageal junction for palliation of dysphagia.

Nelamangala Ramakrishnaiah V, Ramkumar J, Pai D Ecancermedicalscience. 2014; 8:395.

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What is the optimal management of dysphagia in metastatic esophageal cancer?.

Hanna W, Sudarshan M, Roberge D, David M, Waschke K, Mayrand S Curr Oncol. 2012; 19(2):e60-6.

PMID: 22514498 PMC: 3320233. DOI: 10.3747/co.19.892.

Management of upper gastrointestinal cancers.

Melville A, Morris E, Forman D, Eastwood A Qual Health Care. 2001; 10(1):57-64.

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Palliation of dysphagia from inoperable oesophageal carcinoma using Atkinson tubes or self-expanding metal stents.

Davies N, Thomas H, Eyre-Brook I Ann R Coll Surg Engl. 1999; 80(6):394-7.

PMID: 10209405 PMC: 2503156.

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