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Lifelong Consequences of Metabolic Adaptations in Utero?

Overview
Journal Diabetologia
Specialty Endocrinology
Date 1996 Sep 1
PMID 8877299
Citations 1
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Abstract

Dr. Phillips argues that insulin resistance in adult life may be the price the developing fetus has to pay in return for a short-term successful adaptation to undernutrition in utero. The concept is interesting, and, indeed, challenging. There is, however, a strong need for expansion of the existing knowledge of the possible developmental mechanisms involved, especially against the background of the obvious diagnostic and therapeutic gains in this particular group of patients.

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Using fasting plasma glucose concentrations to screen for gestational diabetes mellitus: prospective population based study.

Perucchini D, Fischer U, Spinas G, Huch R, Huch A, Lehmann R BMJ. 1999; 319(7213):812-5.

PMID: 10496823 PMC: 314206. DOI: 10.1136/bmj.319.7213.812.

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