How to Optimize the Effect of 5-fluorouracil Modulated Therapy in Advanced Colorectal Cancer

Overview

Journal Med Oncol

Publisher Springer

Specialty Oncology

Date 1995 Sep 1

PMID 8852401

Citations 1

Authors

P Ragnhammar

H Blomgren

Affiliations

Soon will be listed here.

Citing Articles

Synthesis and antitumor activity of amino acid ester derivatives containing 5-fluorouracil.

Xiong J, Zhu H, Zhao Y, Lan Y, Jiang J, Yang J Molecules. 2009; 14(9):3142-52.

PMID: 19783913 PMC: 6254981. DOI: 10.3390/molecules14093142.

References

Grem J, Chu E, Boarman D, Balis F, Murphy R, McAtee N . Biochemical modulation of fluorouracil with leucovorin and interferon: preclinical and clinical investigations. Semin Oncol. 1992; 19(2 Suppl 3):36-44. View

Punt C, Burghouts J, Croles J, van Liessum P, de Mulder P, Kamm Y . Continuous infusion of high-dose 5-fluorouracil in combination with leucovorin and recombinant interferon-alpha-2b in patients with advanced colorectal cancer. A Multicenter Phase II study. Cancer. 1993; 72(7):2107-11. DOI: 10.1002/1097-0142(19931001)72:7<2107::aid-cncr2820720708>3.0.co;2-m. View

Cadman E, Heimer R, Davis L . Enhanced 5-fluorouracil nucleotide formation after methotrexate administration: explanation for drug synergism. Science. 1979; 205(4411):1135-7. DOI: 10.1126/science.472732. View

Wadler S, Wiernik P . Clinical update on the role of fluorouracil and recombinant interferon alfa-2a in the treatment of colorectal carcinoma. Semin Oncol. 1990; 17(1 Suppl 1):16-21; discussion 38-41. View

Petrelli N, Herrera L, Rustum Y, Burke P, Creaven P, STULC J . A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma. J Clin Oncol. 1987; 5(10):1559-65. DOI: 10.1200/JCO.1987.5.10.1559. View

BERGER S, Jenh C, Johnson L, Berger F . Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells. Mol Pharmacol. 1985; 28(5):461-7. View

Grem J, Jordan E, Robson M, Binder R, HAMILTON J, Steinberg S . Phase II study of fluorouracil, leucovorin, and interferon alfa-2a in metastatic colorectal carcinoma. J Clin Oncol. 1993; 11(9):1737-45. DOI: 10.1200/JCO.1993.11.9.1737. View

Di Costanzo F, Bartolucci R, Calabresi F, Sofra M, Marzola M, Belsanti V . Fluorouracil-alone versus high-dose folinic acid and fluorouracil in advanced colorectal cancer: a randomized trial of the Italian Oncology Group for Clinical Research (GOIRC). Ann Oncol. 1992; 3(5):371-6. DOI: 10.1093/oxfordjournals.annonc.a058209. View

Danhauser L, Freimann Jr J, Gilchrist T, Gutterman J, Hunter C, Yeomans A . Phase I and plasma pharmacokinetic study of infusional fluorouracil combined with recombinant interferon alfa-2b in patients with advanced cancer. J Clin Oncol. 1993; 11(4):751-61. DOI: 10.1200/JCO.1993.11.4.751. View

10.

Petrelli N, Douglass Jr H, Herrera L, Russell D, Stablein D, Bruckner H . The modulation of fluorouracil with leucovorin in metastatic colorectal carcinoma: a prospective randomized phase III trial. Gastrointestinal Tumor Study Group. J Clin Oncol. 1989; 7(10):1419-26. DOI: 10.1200/JCO.1989.7.10.1419. View

11.

ODwyer P, Paul A, Walczak J, Weiner L, Litwin S, Comis R . Phase II study of biochemical modulation of fluorouracil by low-dose PALA in patients with colorectal cancer. J Clin Oncol. 1990; 8(9):1497-503. DOI: 10.1200/JCO.1990.8.9.1497. View

12.

Steinke B, Gunther E, Hirschmann W, Sondern W, Koniczek K, Wander H . Fluorouracil versus folinic acid/fluorouracil in advanced colorectal cancer--preliminary results of a randomized trial. Semin Oncol. 1992; 19(2 Suppl 3):141-7. View

13.

Rougier P, Droz J, Ducreux M, Kac J, Spielmann M, Crespon B . [Treatment of advanced colonic and rectal adenocarcinoma: combination of 5-FU and high-dose folinic acid]. Bull Cancer. 1983; 70(5):434-6. View

14.

Madajewicz S, Petrelli N, Rustum Y, Campbell J, Herrera L, Mittelman A . Phase I-II trial of high-dose calcium leucovorin and 5-fluorouracil in advanced colorectal cancer. Cancer Res. 1984; 44(10):4667-9. View

15.

. Superiority of sequential methotrexate, fluorouracil, and leucovorin to fluorouracil alone in advanced symptomatic colorectal carcinoma: a randomized trial. J Clin Oncol. 1989; 7(10):1437-46. DOI: 10.1200/JCO.1989.7.10.1437. View

16.

Casper E, Vale K, Williams L, Martin D, Young C . Phase I and clinical pharmacological evaluation of biochemical modulation of 5-fluorouracil with N-(phosphonacetyl)-L-aspartic acid. Cancer Res. 1983; 43(5):2324-9. View

17.

BERGER S, Barbour K, Berger F . A naturally occurring variation in thymidylate synthase structure is associated with a reduced response to 5-fluoro-2'-deoxyuridine in a human colon tumor cell line. Mol Pharmacol. 1988; 34(4):480-4. View

18.

Moore E, Friedman J, Valdivieso M, Plunkett W, Marti J, Russ J . Aspartate carbamoyltransferase activity, drug concentrations, and pyrimidine nucleotides in tissue from patients treated with N-(phosphonacetyl)-L-aspartate. Biochem Pharmacol. 1982; 31(20):3317-21. DOI: 10.1016/0006-2952(82)90567-6. View

19.

Horikoshi T, Danenberg K, Stadlbauer T, Volkenandt M, Shea L, Aigner K . Quantitation of thymidylate synthase, dihydrofolate reductase, and DT-diaphorase gene expression in human tumors using the polymerase chain reaction. Cancer Res. 1992; 52(1):108-16. View

20.

Wadler S, Schwartz E, Goldman M, Lyver A, Rader M, Zimmerman M . Fluorouracil and recombinant alfa-2a-interferon: an active regimen against advanced colorectal carcinoma. J Clin Oncol. 1989; 7(12):1769-75. DOI: 10.1200/JCO.1989.7.12.1769. View