Nutrition Support is Not Beneficial and Can Be Harmful in Critically Ill Patients

The introductory remark by Lucretius serves as a reminder that nutrient intake can have very different consequences in different subjects. In the patient with an acute or serious illness, metabolic derangements can transform a substance that is normally a source of energy into a source of metabolic toxins. The potential for organic nutrients to become organic toxins in the diseased host is a phenomenon that deserves more attention in the debate about the value of nutrition support in critically ill patients.