Immunological and Functional Characterization of Mycobacterium Leprae Protein Antigens: an Overview

Overview

Journal Mol Microbiol

Specialties Microbiology
Molecular Biology

Date 1995 Dec 1

PMID 8825083

Citations 12

Authors

J E Thole

B Wieles

T H Ottenhoff

T F Rinke de Wit

Affiliations

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Abstract

A major focus of leprosy research in the last 10 years has been the identification and characterization of antigens of Mycobacterium leprae that interact with antibodies and T cells of the host's immune response. Through the combined efforts of many different laboratories, a substantial number of protein antigens have been identified and characterized. In this MicroReview we present an updated list of M. leprae protein antigens, and, with emphasis on recent developments, summarize what is known regarding their functional and immunological features.

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